Pyridoxine Hydrochloride
Drug interaction with Levodopa.
Peripheral neuropathy, Vitamin B6 deficiency
Hypersensitivity. Patients receiving levodopa.
N/A
Severe peripheral neuropathies (with long-term admin of large doses). Unstable gait, Paresthesias, Decrease sensation, Decreased folic acid
Pyridoxine is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles.
Isoniazid, penicillamine and oral contraceptives may result in greater requirement in pyridoxine dose. Reduces the effects of levodopa, phenobarbitone, altretamine and phenytoin.
Pregnancy Category: A/C-when exceeding RDA recommendations Lactation: Safe
Oral Prophylaxis of vitamin B6 deficiency states Adult: 2.5-10 mg/d. Nausea in Pregnancy 75 mg PO qD
N/A
N/A
Should be taken with food. Preferably taken w/ meals.
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