Jaundice and liver dysfunction (reversible); GI disturbances. IV: Venospasm, thrombophloebitis and haemolysis; hypocalcaemia. SC/IM: Tissue necrosis. Topical: Rashes and irritation.
Pregnancy Category
Name :
Not Classified
Description
FDA has not yet classified the drug into a specified pregnancy category.
Mode of Action
Fusidic acid disrupts translocation of peptide subunits and elongating the peptide chain of susceptible bacteria, thus inhibiting protein synthesis.
Interaction
Synergistic action with antistaphylococcal penicillin. Antagonism with ciprofloxacin.
Pregnancy Category Note
N/A
Adult Dose
Oral
Susceptible infections
Adult: 500 mg tid. May increase to 1 g tid in fulminating infections.
Child Dose
Oral
Susceptible infections
Child: <1 yr: About 15 mg/kg;
1-5 yr: 250 mg;
5-12 yr: 500 mg.
Doses to be taken tid.
Renal Dose
N/A
Administration
Should be taken with food.
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