Vardamate 20mg tab - 20mg

Tablet

Pack Size : 5 Tablet x 1 Strip

Generics : Verdenafil

Manufacturer : Square Pharmaceuticals Ltd.

Best Price * TK 300.00

* Delivery will be done in Dhaka city only.

Alternative Product

Tablet Valenty 10 mg - 10mg Eskayef Pharmaceuticals Ltd.

Tk 35.00

Tablet Valenty 20 mg Tab. - 20mg Eskayef Pharmaceuticals Ltd.

Tk 60.00

Tablet Vardamate 10mg tab - 10mg Square Pharmaceuticals Ltd.

Tk 35.00

More Information About - Vardamate 20mg tab - 20mg

Description

Generic Name

Vardenafil

Precaution

Anatomical deformation of the penis; predisposition to priapism e.g. sickle cell anaemia, multiple myeloma, or leukaemia; bleeding disorders or active peptic ulceration; left ventricular outflow obstruction; elderly (? 65 yr). Discontinue and seek medical advice if there is sudden vision loss or decreased vision in one or both eyes or tinnitus, dizziness or sudden loss or decrease in hearing, while taking vardenafil. May cause dizziness or abnormal vision so avoid driving or operating machinery until effects of vardenafil is known. Seek immediate medical advice if erection last > 4 hr.

Indication

Erectile dysfunction

Contra Indication

Known prolongation of QT interval (congenital or acquired); men for whom sexual intercourse is inadvisable due to CV risk factors; hypotension (systolic <90 mm Hg); hypertension (systolic >170 mm Hg or diastolic >110 mm Hg); recent stroke or MI (within last 6 mth); unstable angina; severe heart failure; end-stage renal disease requiring dialysis; severe hepatic impairment; known degenerative retinal disorders e.g. retinitis pigmentosa. Women, child.

Dose

N/A

Side Effect

Dyspepsia, vomiting, headache, flushing, dizziness, visual disturbances, colour vision changes, raised intra-ocular pressure, nasal congestion, hypersensitivity reactions, nausea, photosensitivity reactions, hypotension, hypertension, priapism, palpitations, myalgia, increased creatinine kinase, sudden decrease or loss of hearing, tinnitus.

Pregnancy Category

Name : B

Description

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Mode of Action

Vardenafil is a phosphodiesterase type-5 inhibitor. It manages erectile dysfunction by increasing the amounts of cyclic guanosine monophosphate (cGMP).

Interaction

May enhance hypotensive effect of ?-blockers. Increased serum concentration with guanylate cyclase stimulators (e.g. riociguat), potent CYP3A4 inhibitors (e.g. ketoconazole) and moderate CYP3A4 inhibitors (e.g. clarithromycin), HIV protease inhibitors (e.g. ritonavir). May prolong Qt interval with class IA (e.g. quinidine, procainamide) or class III (e.g. amiodarone, sotalol) antiarrhythmics. Potentially Fatal: Enhanced hypotensive effect with any form of organic nitrates/nitrites, guanylate cyclase stimulators (e.g. riociguat).

Pregnancy Category Note

Pregnancy category: B Lactation: Unknown whether drug is distributed into breast milk; indicated for males

Adult Dose

Oral Erectile dysfunction Adult: Usual dose: 10 mg as needed; may adjust according to effectiveness and tolerance(range: 5-20 mg). Dose is taken 1hr before sexual intercourse. Max dosing frequency: 1 dose/day Hepatic impairment Child-Pugh class A: Dosage adjustment not necessary Child-Pugh class B: Film-coated tablet, 5 mg PO ~1 hour before sexual activity; not to exceed 10 mg once daily; ODT not recommended Child-Pugh class C: Not recommended

Child Dose

N/A

Renal Dose

Renal impairment Mild, moderate, severe impairment: Dosage adjustment not necessary Hemodialysis: Not recommended

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.