Bonacerin - 50mg

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Diacerein + Glucosamine Sulphate

Manufacturer : Navana Pharmaceuticals Ltd.

Best Price * TK 120.00

* Delivery will be done in Dhaka city only.

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More Information About - Bonacerin - 50mg

Description

Generic Name

Diacerein + Glucosamine Sulphate

Precaution

Caution should be practiced when administering Diacerein + Glucosamine Sulphate in those patients who are allergic to Glucosamine and/or Diacerein or to shellfish (e.g., shrimp, crab); who have diabetes, asthma, alcohol dependence or liver disease. Before taking Diacerein + Glucosamine Sulphate complete blood count, liver function and urinalysis should be monitored regularly.

Indication

Rheumatoid arthritis, Osteoarthritis, Chronic low back pain

Contra Indication

Absorption of Diacerein is reduced if taken with aluminium and/or magnesium hydroxide antacid. Diacerein also increases risk of diarrhea if taken with laxatives, antibiotics. Avoid co-administration with fibers and phytic acids. Diacerein has shown hypersensitivity to anthraquinone derivatives.

Dose

N/A

Side Effect

Diarrhea, constipation, epigastric pain, heart burn, nausea, vomiting, headache, skin rashes, drowsiness, intense yellow coloring of urine.

Pregnancy Category

Name : B+C

Description

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester. Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Diacerein is an anthraquinone derivative that has been used in osteoarthritis. It is thought to act via inhibition of interleukin-1. Glucosamine stimulates the production of proteoglycans and increases sulfate uptake by articular cartilage.

Interaction

Diacerein: Decreased absorption with aluminium and/or magnesium hydroxide antacids. Increased risk of diarrhoea with laxatives, antibiotics. Avoid co-admin with fibres and phytates. Glucosamine: May reduce effect of antidiabetic agents, doxorubicin, etoposide, tenoposide. May enhance anticoagulant activity of warfarin.

Pregnancy Category Note

N/A

Adult Dose

Oral Osteoarthritis Adults: 1 tablet twice daily

Child Dose

Oral Osteoarthritis Children over 12 years and older: 1 tablet twice daily

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <30 25 mg daily.

Administration

Should be taken with food. Take w/ or immediately after meals.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.