Indication
Irritable bowel syndrome (IBS), GI tract spasm
Adult Dose
Oral Irritable bowel syndrome; Gastrointestinal tract spasm Adult: Tablet 135 mg tid, may reduce gradually after several wk when the desired effect has been obtained; As modified-release Capsule: 200 mg bid.
Contraindication
Paralytic ileus.
Mode of Action
Mebeverine is an antispasmodic agent which exerts direct action on the GI smooth muscle.
Precaution
Caution should be exercised in porphyria or allergic reaction to this or any other medicine of this group.
Side Effect
Dizziness, headache, GI disturbances, insomnia, anorexia, decreased heart rate, hypersensitivity (e.g. urticaria, erythematous rash, angioedema).
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