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Clindax Plus - 15gm
Gel
Pack Size :
1 Tube x 1 Packet
Generics :
Clindamycin
Manufacturer :
Opsonin Pharma Ltd.
Best Price *
TK
150.00
* Delivery will be done in Dhaka city only.
Alternative Product
More Information About - Clindax Plus - 15gm
Description
Generic Name
Clindamycin Phosphate 1.2% + Tretinoin 0.025% TopicalPrecaution
Clindacin plus gel is not for oral, ophthalmic, or Intravaginal use. Avoid exposure to sunlight and sunlamps. Wear sunscreen daily. Lactation: excretion in milk unknown; use with cautionIndication
Acne vulgarisContra Indication
Contraindicated in patients with hypersensitivity to clindamycin or tretinoin or any of the ingredients of these medicine.Dose
N/ASide Effect
>10% Erythema (21-35%),Scaling (13-19%),Itching (15-17%) 1-10% Dryness (6%),Irritation (5%),Exfoliation (5%),Erythema (4%),Pruritus (2%),Stinging (2%),Burning (2%),Sunburn (1%),Dermatitis (1%)Pregnancy Category
Name : C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risksMode of Action
Clindamycin: Antibacterial agent that binds to the 50S ribosomal subunits of susceptible bacteria and prevents elongation of peptide chains by interfering with peptidyl transfer, thereby suppressing protein synthesis; reduces surface fatty acids on skin; exact mechanism of action in treating acne unknown Tretinoin: Exact mechanism unknown; appears to cohesiveness of follicular epithelial cells with decrease microcomedo formation; also increases turnover of follicular cells to cause extrusion of comedonesInteraction
Clindamycin: May enhance the action of neuromuscular blocking agents (e.g. atracurium). May antagonise the effects of parasympathomimetics. May competitively inhibit the effects of macrolides, ketolides, streptogramins, linezolid and chloramphenicol. Increased coagulation tests (prothrombin time/INR) and/or bleeding w/ vit K antagonists (e.g. warfarin, acenocoumarol, fluindione). Tretinoin: Enhances percutaneous absorption of minoxidil. Increased risk of fatal thrombotic complications with antifibrinolytic. Increased tretinoin concentrations with azole antifungals. Enhances peeling action of sulphur, resorcinol, benzoyl peroxide, salicylic acid. Increased photosensitivity with photosensitising medications eg, thiazides, tetracyclines, fluoroquinolones, phenothiazines and sulfonamides. Potentially Fatal: Increased risk of intracranial pressure with tetracyclines.Pregnancy Category Note
Pregnancy Category: C Lactation: excretion in milk unknown; use with cautionAdult Dose
Acne Vulgaris Topical Apply a pea-size amount of gel once daily preferably at bed time. Treatment should be continued for 12 weeks.Child Dose
<12 years old: Safety and efficacy not established >12 years: Apply a pea-size amount of gel once daily preferably at bed time.Renal Dose
N/AAdministration
At first wash the face or affected area gently with warm water or soap. When the skin is completely dried (about 30 minutes later) apply a pea-size amount of gel to your fingertip and spread it over your face.Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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