Orbuten 400 mg Cap. - 400mg

Capsule

Pack Size : 4 Capsule x 1 Strip

Generics : Ceftibuten Dihydrate

Manufacturer : Aristopharma Limited

Best Price * TK 480.00

* Delivery will be done in Dhaka city only.

Alternative Product

Capsule Cefamax - 400mg Incepta Pharmaceuticals Ltd.

Tk 120.00

Capsule Cefamax - 200mg Incepta Pharmaceuticals Ltd.

Tk 70.00

More Information About - Orbuten 400 mg Cap. - 400mg

Description

Generic Name

Ceftibuten

Precaution

Hypersensitivity to penicillins; renal impairment; Porphyria. Monitor renal and haematologic status. Lactation: excretion in milk unknown; use with caution

Indication

Respiratory tract infections, Urinary tract infections

Contra Indication

Hypersensitivity to cephalosporins.

Dose

N/A

Side Effect

1-10% Increased BUN (4%),Nausea (4%),Diarrhea (3%),Headache (3%),Increased eosinophils (3%),Decreased hemoglobin (2%),Dyspepsia (2%),Thrombocytosis (2%),Abdominal pain (1%),Dizziness (1%),Increased ALT (1%),Increased bilirubin (1%),Vomiting (1%) <1% Anorexia,Candidiasis,Constipation,Dysuria,Agitation,Fatigue,Insomnia,Irritability,Paresthesia,Rigors,Diaper rash,Urticaria,Dry mouth,Dyspnea,Nasal congestion,Increased transaminases,Increased creatinine,Leukopenia Potentially Fatal: Pseudomembranous colitis.

Pregnancy Category

Name : B

Description

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Mode of Action

Ceftibuten inhibits bacterial cell wall synthesis. It is stable to hydrolysis by many beta-lactamases and has greater activity than 1st or 2nd generation cephalosporins against gm-ve bacteria. It is less active in vitro than cefexime against S. pneumoniae.

Interaction

Enhanced nephrotoxicity of aminoglycosides. Increased serum concentration w/ probenecid. Decreased serum concentration w/ zinc salts.

Pregnancy Category Note

Pregnancy Category: B Lactation: excretion in milk unknown; use with caution

Adult Dose

Oral Respiratory tract infections, Urinary tract infections Adult: 400 mg once daily for 10 days.

Child Dose

Child: <6 months: Safety and efficacy not established 6-12 years old or <45 kg: 9 mg/kg PO qDay; 400 mg/day PO for 10 days maximum >12 years old or >45 kg: As in adults

Renal Dose

Renal impairment: CrCl (ml/min) 30-49 200 mg once daily. 5-29 100 mg once daily.

Administration

Susp: Should be taken on an empty stomach. Take 2 hr before or 1 hr after meals. Cap: May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.