Nizoder 2%gm Cream 30gm

Cream
Pack Size :   1 tube x 1 packet
Best Price * TK  90.00
* Delivery will be done in Dhaka city only.

More Information About - Nizoder 2%gm Cream 30gm

Description

Generic Name

Ketoconazole cream

Precaution

In patients who have been on prolonged treatment with topical corticosteroids, it is recommended that the steroid therapy be gradually withdrawn over a period of 2 to 3 weeks, while using Ketoconazole cream to prevent any potential rebound effect. Avoid contact with the eyes.

Indication

Seborrheic dermatitis of the scalp, Pityriasis versicolor

Contra Indication

Known hypersensitivity to ketoconazole or any of the excipients.

Dose

N/A

Side Effect

1-10% Irritation, severe,Pruritus,Stinging

Pregnancy Category

Name : Not Classified
Description
FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Ketoconazole interferes w/ biosynthesis of triglycerides and phopholipids by blocking fungal CYP450, thus altering cell membrane permeability in susceptible fungi. It also inhibits other fungal enzymes resulting in the accumulation of toxic concentrations of hydrogen peroxide.

Interaction

N/A

Pregnancy Category Note

Pregnancy There are no available data on use in pregnant women to identify a drug-associated risk of birth defects, miscarriage or adverse maternal or fetal outcomes; no reproductive studies in animals have been performed; in animal reproduction studies with pregnant mice, rats and rabbits both embryotoxic and developmental effects (structural abnormalities) were observed following oral dosing of ketoconazole during organogenesis; assuming equivalent systemic absorption of topical and oral ketoconazole doses and a maximum recommended human dose (MRHD) of 8 grams (equivalent to 160 mg ketoconazole), embryotoxic effects were observed at 0.8 to 2.4 times the MRHD and developmental effects were observed at 4.8 times the MRHD. Lactation There is no information available on presence of ketoconazole in human milk, or effects on breastfed child, or effects on milk production after topical application to women who are breastfeeding; in animal studies ketoconazole was found in milk following oral administration; the developmental and health benefits of breastfeeding should be considered along with the mother?s clinical need for therapy and any potential adverse effects on breastfed infant from treatment or from underlying maternal condition.

Adult Dose

Topical Seborrheic Dermatitis Cream: Apply q12hr for 4 weeks or until clear Tinea Corporis, Tinea Cruris, Tinea Pedis Cream: Apply qDay for 2 weeks (6 weeks for tinea pedis), covering affected area

Child Dose

Seborrheic Dermatitis <12 years: Safety and efficacy not established >12 years (cream): Apply to affected area q12hr x4 weeks

Renal Dose

N/A

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.

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