Troniz 500mg

Tablet

Pack Size : 10 Tablet x 1 strip

Generics : Ornidazole

Manufacturer : Unimed & Unihealth Manufacturers Ltd.

Best Price * TK 65.00

* Delivery will be done in Dhaka city only.

Alternative Product

Tablet OR - 500mg Zenith Pharmaceuticals Ltd.

Tk 5.00

Tablet Ornid - 500mg Drug International Ltd.

Tk 7.05

Tablet Robic - 500mg Square Pharmaceuticals Ltd.

Tk 7.02

More Information About - Troniz 500mg

Description

Generic Name

Ornidazole

Precaution

Renal and hepatic impairment. CNS diseases e.g. epilepsy or multiple sclerosis. May impair ability to drive or operate machinery. Pregnancy and lactation.

Indication

Amoebiasis, Hereditary angioedema, Trichomoniasis, Anaerobic bacterial infections, Amoebic dysentery, Surgical Prophylaxis,

Contra Indication

Hypersensitivity to ornidazole or to other nitroimidazole derivatives.

Dose

N/A

Side Effect

Somnolence, headache, nausea, vomiting, dizziness, tremor, rigidity, poor coordination, seizures, tiredness, vertigo, temporary loss of consciousness and signs of sensory or mixed peripheral neuropathy, taste disturbances, abnormal LFTs, skin reactions.

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Ornidazole is a 5-nitroimidazole derivative active against protozoa and anaerobic bacteria. It is converted to reduction products that interact with DNA to cause destruction of helical DNA structure and strand leading to a protein synthesis inhibition and cell death in susceptible organisms.

Interaction

May decrease absorption of oral fat-soluble vitamins, amiodarone, propafenone. May decrease plasma levels of ciclosporin. May alter the effects of warfarin (monitor INR). May elevate plasma levels of pravastatin.

Pregnancy Category Note

N/A

Adult Dose

Oral Amoebiasis Adult: 0.5 g bid for 5-10 days. Amoebic dysentery Adult: 1.5 g as a single daily dose for 3 days. Alternatively for patients >60 kg: 1 g bid for 3 days. Giardiasis Adult: 1-1.5 g as a single daily dose for 1-2 days. Trichomoniasis Adult: 1.5 g as a single daily dose or 0.5 g bid for 5 days. Treat sexual partners concomitantly. Hepatic impairment: Severe: Double the interval between doses.

Child Dose

Oral Amoebiasis Child: 25 mg/kg as a single daily dose for 5-10 days. Amoebic dysentery Child: 40 mg/kg daily. Giardiasis Child: 30-40 mg/kg daily. Trichomoniasis Child: 25 mg/kg as a single dose.

Renal Dose

Renal impairment: Haemodialysis patients: Give a supplemental dose (50% of the usual dose) before dialysis.

Administration

Should be taken with food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.