More Information About - Urodart 500 mcg Cap. 500mcg
Description
Generic Name
Dutasteride
Precaution
Excreted in semen therefore use of condom is recommended. Women of childbearing potential should avoid handling dutasteride capsules. Advisable to exclude other causes of benign prostatic hypertrophy (e.g. prostate cancer, infection) before initiating therapy.
Lactation: Excretion in milk unknown/contraindicated
Indication
Benign prostatic hyperplasia (BPH)
Contra Indication
Severe liver impairment; pregnant women, children, adolescent.
Dose
N/A
Side Effect
1-10%
Impotence,Decreased libido,Ejaculation disorder,Breast disorders/gynecomastia
<1%
Dizziness
Frequency Not Defined
Cardiac failure,Prostate cancer (high grade)
Pregnancy Category
Name :
X
Description
Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.
Mode of Action
Dutasteride has antiandrogenic properties. It inhibits 5alpha-reductase, thus preventing the conversion of testosterone to 5?-dihydrotestosterone which is the main androgen involved in causing prostate enlargement.
Interaction
Plasma concentrations may be increased when used concomitantly w/ moderate or potent CYP3A4 inhibitors.
Pregnancy Category Note
Pregnancy category: X
Lactation: Excretion in milk unknown/contraindicated
Adult Dose
Oral
Benign prostatic hyperplasia
Adult: 500 mcg once daily for at least 6 mth.
Hepatic impairment: Severe: Contraindicated.
Child Dose
N/A
Renal Dose
Renal impairment: Dose adjustment not necessary
Administration
May be taken with or without food.
Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.