Nimocal 30 mg Tab. 30mg

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Nimodipine

Manufacturer : Square Pharmaceuticals Ltd.

Best Price * TK 50.30

* Delivery will be done in Dhaka city only.

Alternative Product

Tablet Nimocal 30 mg Tab Square Pharmaceuticals Ltd.

Tk 5.03

More Information About - Nimocal 30 mg Tab. 30mg

Description

Generic Name

Nimodipine

Precaution

Patients w/ cerebral oedema or severely raised intracranial pressure. Contents of oral capsules should be given only by mouth or through a feeding tube. It must never be administered IV or by any other parenteral route. Hepatic and renal impairment. Pregnancy and lactation. Monitoring Parameters Careful monitoring of BP and pulse rate. Lactation: unknown; avoid

Indication

Subarachnoid haemorrhage, Stroke prevention

Contra Indication

Use w/in 1 mth of MI or an episode of unstable angina. Concomitant use w/ potent CYP3A4 inhibitors (e.g. clarithromycin, ritonavir, ketoconazole, nefazodone).

Dose

N/A

Side Effect

1-10% Reduction in systemic blood pressure (1-8%),Diarrhea (2-4%),Headache (1-4%),Abdominal discomfort (2%),Rash (1-2%) <1% Heart failure,Arrhythmia,Anemia,ECG abnormalities,GI hemorrhage,Hepatitis,Jaundice,Thrombocytopenia,Vomiting,Thrombosis,Rebound vasospasm Potentially Fatal: Angina/MI, symptomatic hypotension.

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Nimodipine inhibits inflow of Ca ions into cells by blocking Ca channels or select voltage-sensitive areas resulting in relaxation of vascular smooth muscle and myocardium during depolarisation. Nimodipine has greater action on the cerebral vessels because of its high lipophilicity.

Interaction

Plasma concentration and efficacy may be significantly reduced when administered w/ strong CYP3A4 inducers (e.g. rifampicin, carbamazepine, phenobarbital, phenytoin). May increase serum levels and toxicity of phenytoin. Increased plasma concentrations w/ cimetidine or sodium valproate. Potentially Fatal: Increased risk of significant hypotension w/ concomitant potent CYP3A4 inhibitors (e.g. clarithromycin, ritonavir, ketoconazole, nefazodone).

Pregnancy Category Note

N/A

Adult Dose

Oral Prophylaxis of neurological deficit following subarachnoid haemorrhage Adult: 60 mg 4 hrly beginning w/in 4 days of onset of haemorrhage and continued for 21 consecutive days. Hepatic impairment: Initially, 30 mg 4 hrly.

Child Dose

N/A

Renal Dose

N/A

Administration

Cap: Should be taken on an empty stomach. Take on an empty stomach 1 hr before or 2 hr after meals. Tab: May be taken with or without food. Take consistently, either always w/ or always w/o meals.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.