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Maxpime IV/IM 1gm/vial
Injection
Pack Size :
1 Bottle x 1 Packet
Generics :
Cefepime
Manufacturer :
Square Pharmaceuticals Ltd.
Best Price *
TK
551.65
* Delivery will be done in Dhaka city only.
Alternative Product
More Information About - Maxpime IV/IM 1gm/vial
Description
Generic Name
CefepimePrecaution
Renal impairment; history of penicillin or cephalosporin allergy; lactation, pregnancy. Caution when used in patients with history of GI diseases, especially colitis. May decrease prothrombin activity; monitor prothrombin time in patients with poor nutritional state, renal or hepatic impairment and those on prolonged treatment. Prolonged treatment may result in overgrowth of nonsusceptible organisms, resulting in superinfection. Consider the possibility of Clostridium difficile associated diarrhoea in patients who present with diarrhoea after treatment. Caution when used in patients with a history of seizures. Lactation: Drug enters breast milk; use with cautionIndication
Skin and skin structure infections, Urinary tract infection, Nosocomial pneumonia, Multiple drug resistant pneumonia, NeutropeniaContra Indication
Hypersensitivity to cefepime or other cephalosporins.Dose
N/ASide Effect
>10% Positive Coombs test result without hemolysis (16%) 1-10% Rash (1-4%),Elevated alanine aminotransferase (3%),Hypophosphatemia (3%),Diarrhea (<3%),Eosinophilia (2%),Erythema at injection site (2%),Normal partial thromboplastin time (PTT) (2%),Nausea or vomiting (<2%),Fever (1%),Headache (1%),Pain (1%),Pruritus (1%) <1% Agranulocytosis,Anaphylactic shock,Anaphylaxis,Coma,Encephalopathy,Hallucinations,Leukopenia,Myoclonus,Neuromuscular excitability,Neutropenia,Seizures,ThrombocytopeniaPregnancy Category
Name : B
Description
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.Mode of Action
Cefepime is a 4th generation cephalosporin which inhibits the final transpeptidation step of peptidoglycan synthesis in bacterial cell wall by binding to one or more of the penicillin-binding proteins (PBPs).Interaction
Increased potential for nephrotoxicity and ototoxicity of aminoglycosides. Increased risk of nephrotoxicity w/ potent diuretics (e.g. furosemide).Pregnancy Category Note
Pregnancy category: B Lactation: Drug enters breast milk; use with cautionAdult Dose
Adult: IV UTI 0.5-1 g 12 hrly for 7-10 days. Empirical therapy for febrile neutropenia 2 g 8 hrly for 7 days or until resolution of neutropenia. Moderate to severe pneumonia 1-2 g 12 hrly for 10 days. Complicated intra-abdominal infections 2 g 12 hrly for 7-10 days. Uncomplicated skin and skin structure infections 2 g 12 hrly for 10 days.Child Dose
Child: IV, IM 100 mg/kg/day q12h 150 mg/kg/day empiric therapy of fever with neutropenia q8h 2 mth - 16 yr: >40 kg: 50 mg/kg every 12 hr for 7-10 days for Uncomplicated and Complicated Urinary Tract Infections (including pyelonephritis), Uncomplicated Skin and Skin Structure Infections and Pneumonia.. May be given via direct inj over 5 minutes or infuse over 30 minutes. For empiric therapy for febrile neutropenic patients 2 mth - 16 yr: <40 kg: 50 mg/kg every 8 hr for 7 days or until neutropenia resolves.Renal Dose
Renal impairment: Haemodialysis: 1 g on the 1st day of treatment, followed by 0.5 g 24 hrly; dose should be given after haemodialysis on dialysis days and preferably at the same time each day. CAPD: Adult dose 48 hrly. CrCl (ml/min) <10 0.25-0.5 g 24 hrly. 11-29 0.5-1 g 24 hrly. 30-60 0.5-2 g 24 hrly.Administration
Reconstitution: IV infusion: Add 5 mL, 10 mL, or 10 mL of a compatible IV soln to a vial labeled as containing 500 mg, 1 g, or 2 g, respectively, to provide soln containing approx 100 mg/mL, 100 mg/mL, or 160 mg/mL of the drug, respectively. The appropriate dose of the drug should then be added to a compatible IV soln. IM inj: Add 1.3 mL or 2.4 mL of an appropriate diluent (e.g. sterile water for inj, NaCl 0.9%) to a vial labeled as containing 500 mg or 1 g respectively, to provide a soln containing approx 280 mg/mL. IV Administration Infuse intermittently over 30 minutes IM Administration Inject deeply Give IM only in mild-to-moderate UTI due to E coliDisclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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