Dostimid 60mg

Tablet

Pack Size : 10 Tablet x 1 strip

Generics : Pyridostigmine

Manufacturer : Unimed & Unihealth Manufacturers Ltd.

Best Price * TK 220.00

* Delivery will be done in Dhaka city only.

Alternative Product

More Information About - Dostimid 60mg

Description

Generic Name

Pyridostigmine

Precaution

Patient w/ bronchial asthma, COPD, bradycardia, cardiac arrhythmias, vagotonia, peptic ulcer, epilepsy or parkinsonism, hyperthyroidism. Renal impairment. Childn. Pregnancy and lactation. Monitoring Parameters Monitor cholinergic reaction particularly in IV admin.

Indication

Reversal of neuromuscular blockade, Myasthenia gravis, Paralytic ileus, post-operative urinary retention

Contra Indication

Mechanical GI or urinary obstruction.

Dose

N/A

Side Effect

Nausea, vomiting, diarrhoea, increased peristalsis and bronchial secretions, miosis, excessive salivation and sweating, abdominal cramps, bradycardia, bronchospasm, skin rash, muscle spasm, fasciculation, muscle weakness. Potentially Fatal: Resp paralysis, cardiac arrest, pulmonary oedema.

Pregnancy Category

Name : B

Description

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Mode of Action

Pyridostigmine bromide facilitates impulse transmission across the myoneural junction by inhibiting the destruction of acetylcholine by acetylcholinesterase. It also has direct cholinomimetic effect on skeletal muscles.

Interaction

May exacerbate night vision problems w/ anti-glaucoma drugs. Antagonises the effect of non-depolarising muscle relaxants (e.g. pancuronium, vecuronium). Prolongs the effect of depolarising muscle relaxants (e.g. suxamethonium).

Pregnancy Category Note

Pregnancy Category: B Lactation: Compatible

Adult Dose

Oral Myasthenia gravis Adult: 30-120 mg in divided doses, up to a total daily dose of 0.3-1.2 g. Paralytic ileus and postoperative urinary retention Adult: 60-240 mg daily.

Child Dose

Oral Myasthenia gravis Child: <6 yr Initially, 30 mg; 6-12 yr Initially, 60 mg. Doses are repeated throughout the day up to a usual total daily dose of 30-360 mg, w/ increments of 15-30 mg daily until a satisfactory response is obtained. Paralytic ileus and postoperative urinary retention Child: 15-60 mg daily.

Renal Dose

Renal impairment: Lower initial dose may be needed, titrate to desired effect.

Administration

Should be taken with food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.