Vib 20mg

Tablet

Pack Size : 10 Tablet x 1 strip

Generics : Valdecoxib

Manufacturer : Acme Laboratories Ltd.

Best Price * TK 1,500.00

* Delivery will be done in Dhaka city only.

Alternative Product

Tablet Vib 10mg Acme Laboratories Ltd.

Tk 150.00

More Information About - Vib 20mg

Description

Generic Name

Valdecoxib

Precaution

Mild to moderate hepatic impairment; history of ulcer disease or GI bleeding; dehydration, hypertension, history of heart failure, left ventricular dysfunction, pre-existing oedema. Monitor Hb or haematocrit values for signs and symptoms of anaemia.

Indication

Osteoarthritis, Rheumatoid arthritis, Dysmenorrhoea

Contra Indication

Hypersensitivity to sulfonamides, NSAIDs and other COX 2 inhibitors; asthma, urticaria; severe hepatic impairment; pregnancy (third trimester); lactation. Active GI bleed or ulceration, severe CHF, inflammatory bowel disease.

Dose

N/A

Side Effect

Hypertension, back pain, myalgia, peripheral oedema, influenza-like symptoms, dizziness, headache, abdominal fullness, abdominal pain, diarrhoea, dyspepsia, flatulence, nausea, myalgia, sinusitis. Potentially Fatal: Toxic epidermal necrolysis, exfoliative dermatitis.

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Valdecoxib acts by selectively inhibiting prostaglandin synthesis primarily by blocking cyclooxygenase (COX-2) enzyme. It was withdrawn worldwide, following risk of serious skin reactions and cardiovascular side effects.

Interaction

Concomitant admin of aspirin may result in an increased risk of GI ulceration and complications. It decreases the antihypertensive effect of antihypertensives e.g. ACE inhibitors. It increases plasma conc of dextromethorphan. It significantly decreases lithium serum clearance and renal clearance.

Pregnancy Category Note

N/A

Adult Dose

Oral Osteoarthritis, Rheumatoid arthritis Adult: 10 mg once daily. Dysmenorrhoea Adult: 20 mg bid. Hepatic Impairment Child-Pugh scale 7-9: Initiate with caution. Child-Pugh scale >10: Avoid.

Child Dose

N/A

Renal Dose

Renal Impairment CrCl Dosage <30 Initiate with caution.

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.