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Pronil DS 1gm
Tablet
Pack Size :
2 Tablet x 1 strip
Generics :
Secnidazole
Manufacturer :
Acme Laboratories Ltd.
Best Price *
TK
193.28
* Delivery will be done in Dhaka city only.
More Information About - Pronil DS 1gm
Description
Generic Name
SecnidazolePrecaution
Avoid alcohol and disulfiram. Avoid in patients with history of blood disorders.Indication
Giardiasis, Amoebiasis, TrichomoniasisContra Indication
Hypersensitivity; pregnancy (1st trimester) and lactation.Dose
N/ASide Effect
Nausea, gastralgia, change of taste, metallic taste, stomatitis, urticaria, rashes, leucopenia. Rarely vertigo, moderate neurological, digestive disturbances.Pregnancy Category
Name : Not Classified
Description
FDA has not yet classified the drug into a specified pregnancy category.Mode of Action
Secnidazole is active against E histolytica, G lamblia, T vaginalis, Clostridium spp, B fragilis, Gardnerella spp. The drug enters the microorganisms by diffusion and is reduced intracellularly by low oxidation-reduction potential ferredoxin which then result in DNA damage.Interaction
Concurrent disulfiram admin may cause psychotic reactions. Disulfiram-like reactions with alcohol. Cimetidine may prolong half-life. Potentially Fatal: May potentiate anticoagulant effect of warfarin and increase risk of haemorrhage.Pregnancy Category Note
Pregnancy Data with secnidazole use in pregnant women are insufficient to inform a drug-associated risk of adverse developmental outcomes In animal reproduction studies, there were no adverse developmental outcomes when secnidazole was administered orally to pregnant rats and rabbits during organogenesis at doses up to 4 times the clinical dose Lactation There is no information on the presence of secnidazole in human milk, the effects on the breastfed child, or the effects on milk production Other nitroimidazole derivatives are present in human milk Because of the potential for serious adverse reactions, including tumorigenicity, advise patients that breastfeeding is not recommended during treatment with secnidazole and for 96 hr after administration of secnidazoleAdult Dose
Oral Trichomoniasis; Amoebiasis; Giardiasis Adult: 2 g as a single dose. Severe invasive amoebiasis Adult: 1.5 g daily as single or in divided doses for 5 days.Child Dose
Oral Trichomoniasis; Amoebiasis; Giardiasis Child: 30 mg/kg as a single dose. Severe invasive amoebiasis Child: 30 mg/kg daily for 5 days.Renal Dose
N/AAdministration
N/ADisclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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