Generic Name

Travoprost 0.004% Eye prep

Precaution

Aphakic patient, pseudophakic patient w/ torn posterior lens capsule or anterior chamber lenses, or w/ known risk factor for cystoid macular oedema. Patient w/ history of intraocular inflammation (e.g. uveitis, iritis). Pregnancy and lactation. Patient Counselling Remove contact lenses prior to admin and reinsert after 15 min. Lactation: distributed in milk in animals; caution if used in nursing women

Indication

Ocular hypertension, Open-angle glaucoma

Contra Indication

Hypersensitivity, Pregnancy

Dose

N/A

Side Effect

>10% Increased pigmentation of iris & periorbital tissue & increased pigmentation, thickening, elongation & growth of eyelashes (59%),Ocular hyperemia (35-50%) 1-10% Decreased visual acuity (5-10%),Ocular discomfort (5-10%),Foreign body sensation (5-10%),Pain (5-10%),Pruritus (5-10%),Abnormal vision (1-4%),Blepharitis (1-4%),Blurred vision (1-4%),Cataract (1-4%),Conjunctivitis (1-4%),Dry eye (1-4%),Iris discoloration (1-4%),Keratitis (1-4%),Lid margin crusting (1-4%),Photophobia (1-4%),Subconjunctival hemorrhage (1-4%),Tearing (1-4%)

Pregnancy Category

Mode of Action

Travoprost, a synthetic analogue of prostaglandin F2α, reduces intraocular pressure by increasing uveoscleral outflow of aqueous humour.

Interaction

Reduced therapeutic effect w/ NSAIDs.

Pregnancy Category Note

Pregnancy Category: C Lactation: distributed in milk in animals; caution if used in nursing women

Adult Dose

Ophthalmic Ocular hypertension; Open-angle glaucoma Adult: As 0.004% soln: Instill 1 drop in the conjunctival sac of the affected eye(s) once daily, preferably in the evening.

Child Dose

Safety and efficacy not established

Renal Dose

N/A

Administration

N/A