Generic Name

Azithromycin 1% Eye drop

Precaution

Anaphylaxis and hypersensitivity have been reported with systemic use of azithromycin . Growth of resistant organisms may occur with prolonged use. patients should not wear contact lenses if they have signs or symptoms of bacterial conjunctivitis. Lactation: Excretion in milk unknown; use with caution

Indication

Bacterial Conjunctivitis, Neonatal Conjunctivitis, Blepharitis

Contra Indication

Known hypersensitivity to azithromycin, erythromycin, any macrolide or ketolide antibiotic. Coadministration w/ pimozide. History of cholestatic jaundice/hepatic dysfunction associated w/ prior use of azithromycin.

Dose

N/A

Side Effect

1-10% Eye irritation (1-2%) <1% Anaphylaxis,Contact dermatitis,Corneal erosion,Dry eye,Rash,Urticaria,Dygeusia,Nasal congestion,Ocular discharge,Punctate keratitis,Sinusitis

Pregnancy Category

Mode of Action

Azithromycin is a semisynthetic azalide antibiotic. It blocks transpeptidation by binding to 50s ribosomal subunit of susceptible organisms and disrupting RNA-dependent protein synthesis at the chain elongation step.

Interaction

N/A

Pregnancy Category Note

Pregnancy Category: B Lactation: Excretion in milk unknown; use with caution

Adult Dose

Bacterial conjunctivitis Adult: Instill 1 drop in the affected eye(s) bid for 2 days, then once daily for the next 5 days.

Child Dose

Bacterial conjunctivitis Child >1 year: Instill 1 drop in the affected eye(s) bid for 2 days, then once daily for the next 5 days.

Renal Dose

N/A

Administration

N/A