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Breon - 25/100 mcg
Capsule
Pack Size :
10 Capsule x 1 Strip
Generics :
Vilanterol Trifenatate + Fluticasone Furoate
Manufacturer :
ACI Limited
Best Price *
TK
220.00
* Delivery will be done in Dhaka city only.
Alternative Product
More Information About - Breon - 25/100 mcg
Description
Generic Name
Vilanterol + Fluticasone furoatePrecaution
Do not use to treat acute asthma symptoms or an acute exacerbation in COPD. Discontinue immediately if paradoxical bronchospasm occurs. Cardiac arrhythmias (eg, supraventricular tachycardia & extrasystoles). Systemic effects may occur w/ inhaled corticosteroids particularly at high doses prescribed for long periods. Patient w/ pulmonary TB or in patients w/ chronic or untreated infections. Visual disturbances may occur. History of or w/ risk factors for DM. Pneumonia in patients w/ COPD & asthma. Immunosuppression. Concomitant use of long-acting ?2-adrenergic agonists. Hepatic impairment. Pregnancy & lactation. Childn <12 yr.Indication
Chronic Obstructive Pulmonary Disease (COPD), AsthmaContra Indication
Hypersensitivity to drug, any components/excipients, or milk proteins Primary treatment of status asthmaticus or other acute episodes of COPD or asthma where intensive measures are requiredDose
N/ASide Effect
1-10% Nasopharyngitis (9%) Upper respiratory infection (7%) Headache (7%) Oropharyngeal candidiasis (5%)Pregnancy Category
Name : Not Classified
Description
FDA has not yet classified the drug into a specified pregnancy category.Mode of Action
Vilanterol: Long-acting selective beta2-adrenergic agonist (LABA); stimulates intracellular adenyl cyclase resulting in increased cAMP levels causing bronchial smooth muscle relaxation; also inhibits release of mediators of immediate hypersensitivity from cells, especially from mast cells Fluticasone furoate (FF): Long-acting inhaled trifluorinated corticosteroid with potent anti-inflammatory activity; inhibits multiple cell types (eg, mast cells, eosinophils, basophils, lymphocytes, macrophages, neutrophils) and mediator production or secretion (eg, histamine, eicosanoids, leukotrienes, cytokines) involved in the asthmatic responseInteraction
Weakened or antagonized effect w/ ?-adrenergic blockers. Increased systemic exposure w/ strong CYP3A4 inhibitors (eg, ketoconazole, ritonavir). Potentiated adverse reactions w/ other sympathomimetic drugs.Pregnancy Category Note
Pregnancy Disease-associated maternal and/or embryofetal risk; in women with poorly or moderately controlled asthma, there is increased risk of several perinatal outcomes such as pre-eclampsia in mother and prematurity, low birth weight, and small for gestational age in the neonate; pregnant women should be closely monitored and medication adjusted as necessary to maintain optimal control of asthma Labor and Delivery: There are no human studies evaluating effects during labor and delivery; because of potential for beta-agonist interference with uterine contractility, use during labor should be restricted to those patients in whom benefits clearly outweigh risks Lactation There is no information available on presence of fluticasone furoate or vilanterol in human milk; effects on breastfed child, or effects on milk production; low concentrations of other inhaled corticosteroids have been detected in human milk; developmental and health benefits of breastfeeding should be considered along with mother?s clinical need for therapy and any potential adverse effects on breastfed child from fluticasone furoate or vilanterol or from underlying maternal conditionAdult Dose
Chronic Obstructive Pulmonary Disease Indicated for long-term, once-daily, maintenance treatment of airflow obstruction with COPD, including chronic bronchitis and/or emphysema; also approved to reduce COPD exacerbations 25 mcg/100 mcg (1 actuation) inhaled PO once daily Asthma Indicated for once-daily treatment of asthma for patients not adequately controlled on a long-term asthma control medication (eg, inhaled corticosteroid), or whose disease severity clearly warrants initiation of treatment with both an inhaled corticosteroid and a long-acting beta agonist (LABA) Prescribe strength (25 mcg/100 mcg or 25 mcg/200 mcg per actuation) once daily via oral inhalation Hepatic impairment: No dosage adjustment requiredChild Dose
N/ARenal Dose
Renal impairment: No dosage adjustment requiredAdministration
After inhalation, rinse mouth with water and expectorate to help reduce risk of oropharyngeal candidiasis Take at same time each day Do not exceed 1 administration/24 hrDisclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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