Cifibet - 100mg

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Ciprofibrate

Manufacturer : Eskayef Pharmaceuticals Ltd.

Best Price * TK 150.00

* Delivery will be done in Dhaka city only.

Alternative Product

More Information About - Cifibet - 100mg

Description

Generic Name

Ciprofibrate

Precaution

Patient w/ hypoalbuminaemia, nephrotic syndrome, hypothyroidism, alcohol abuse, history of hereditary muscular disorder, previous toxicity w/ other fibrates. Mild to moderate hepatic and renal impairment. Monitor for renal function. Perform periodic LFT every 3 mth for the 1st yr of treatment. Monitor for serum creatine phosphokinase (CPK) levels of patients reporting unexplained muscle pain, tenderness, or weakness.

Indication

Hypertriglyceridaemia, Mixed hyperlipidaemia

Contra Indication

Severe hepatic impairment. Severe renal impairment. Pregnancy and lactation, or when pregnancy is suspected. Concurrent use with another fibrate. Hypersensitivity to the active substance or to any component of the product.

Dose

N/A

Side Effect

Urticaria, rashes, pruritus, eczema; elevated CPK levels, myalgia, myositis; headache, vertigo; nausea, vomiting, anorexia, diarrhoea, dyspepsia, abdominal pain; thrombocytopenia. Rarely, photosensitivity, alopecia, rhabdomyolysis, dizziness, somnolence, impotence, cholestasis, cytolysis, pneumonitis, pulmonary fibrosis, fatigue, leukocytopenia, pancreatitis, peripheral neuropathy.

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Ciprofibrate is a fibric acid derivative that has a marked hypolipidaemic action. It reduces both LDL and VLDL cholesterols, leading to reduced levels of triglycerides, while increasing the HDL cholesterol levels.

Interaction

Increased risk of muscle effects esp rhabdomyolysis w/ HMG-CoA reductase inhibitors. Reduced absorption w/ cholestyramine and colestipol. May increase the effects of phenytoin, tolbutamide and other sulphonylurea derivatives, and coumarin-like anticoagulants. May potentiate the effect of warfarin. Potentially Fatal: Increased risk of rhabdomyolysis and myoglobinuria w/ other fibrates.

Pregnancy Category Note

Pregnancy There is no evidence that ciprofibrate is teratogenic, but signs of toxicity at high doses were observed in teratogenicty tests in animals. As there are no data on its use in human pregnancy ciprofibrate is contraindicated during pregnancy. Lactation Ciprofibrate is excreted in the breast milk of lactating rats. As there are no data on its use in lactation, ciprofibrate is contraindicated in nursing mothers.

Adult Dose

Oral Hyperlipidaemias Adult: 100 mg daily. Hepatic Impairment Severe: Contraindicated.

Child Dose

N/A

Renal Dose

Renal Impairment CrCl (mL/min) Dosage <30 Contraindicated. 30-80 Reduce dose to 100 mg every other day.

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.