Indications

Undenatured Collagen capsule is indicated for-

• Osteoarthritis
• Rheumatoid arthritis
• Joint pain & inflammation
• Difficulties in flexibility & mobility
• Joint discomfort & stiffness (knee extension)
• Impaired joint function
• Strenuous exercise & sports

Pharmacology

Undenatured Type II Collagen manufactured from chicken sternum cartilage via a proprietary low-temperature, non-enzymatic production technique that maintains the native triple helix molecular arrangement and biological activity. Collagen II that has not been denatured has a distinct mode of action. Oral toleration is triggered by active binding sites called epitopes found in undenatured collagen II molecules. Active epitopes of undenatured collagen II engage with Peyer's patches (lymphoid tissue) in the small intestine to release collagen-specific regulatory T-cells through the oral tolerization process. T-cells that are specific for collagen move to joint regions and block the release of T-c.

Preventing the release of T-cells prevent the secretion of collagenase enzymes by macrophages responsible for breakdown of collagen in joint cartilage. It also slows the production of inflammatory cytokines resulting in reduction of inflammation, halting the erosion of joint cartilage and promote cartilage rebuilding. Undenatured Type II Collagen supports joint function, mobility and flexibilityand  also improves knee extension by up to 10% for better range of motion. It also relieves joint pain due to strenuous exercise.

Dosage & Administration

Orally 1 capsule daily with water or as directed by the physician

Contraindications

Contraindicated in patients with known hypersensitivity to chicken or egg.

Side Effects

Pregnancy & Lactation

Lack of scientific evidence on the use of undenatured collagen II during pregnancy or lactation.

Storage Conditions

Keep away from direct sunlight and moisture, Store below 30°C temperature in cool and dry place. Keep the medicine out of reach of children.