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Danflex - 25mg
Capsule
Pack Size :
10 Capsule x 1 Strip
Generics :
Dantrolene Sodium
Manufacturer :
Opsonin Pharma Ltd.
Best Price *
TK
100.00
* Delivery will be done in Dhaka city only.
More Information About - Danflex - 25mg
Description
Generic Name
Dantrolene SodiumPrecaution
Perform LFTs before and during treatment. Increased risk of liver injury in patients >30 yr, female patients especially those on oestrogen therapy, history of liver disease or patients with daily dose >400 mg. Cardiac or pulmonary disorders. Pregnancy. Lactation: enters breast milk/not recommendedIndication
Muscle tightness, muscle cramping (spasms), muscle pain caused by spinal cord injury, stroke, cerebral palsy, multiple sclerosis.Contra Indication
Active liver disease; acute muscle spasm; patients who use their spasticity to maintain posture or function. Lactation.Dose
N/ASide Effect
Fatigue, muscle weakness/pain. GI disturbances, CNS effects, tachycardia, unstable BP, dyspnoea, drowsiness, rashes, pruritus, chills and fever, visual disturbances, dysphagia, speech disturbances; haematuria, crystalluria, urinary frequency, retention and incontinence. Increased serum AST (SGOT), ALT (SGPT), alkaline phosphatase, LDH, BUN, and total serum bilirubin concentrations, Difficult erection, Abnormal hair growth, Aplastic anemia, Anemia, Leukopenia, Lymphoma, Thrombocytopenia Potentially Fatal: Hepatotoxicity, pleural effusion with pericarditis.Pregnancy Category
Name : C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risksMode of Action
Dantrolene has a direct action on skeletal muscle. It uncouples muscular contraction from excitation, probably by interfering with calcium release from sarcoplasmic reticulum.Interaction
CNS depressants; oestrogens; calcium-channel blockers. CNS effects enhanced by alcohol or CNS depressants.Pregnancy Category Note
Pregnancy Category: C Lactation: enters breast milk/not recommendedAdult Dose
Oral Spasticity Adult: Initially, 25 mg daily increased gradually at 7-day intervals over 7 wk. Discontinue if no response after 45 days of treatment. Max: 100 mg 4 times daily.Child Dose
Oral Spasticity Child: Initially, 0.5 mg/kg once daily, may increase gradually to 2 mg/kg 3-4 times daily. Max: 100 mg 4 times daily.Renal Dose
N/AAdministration
May be taken with or without food.Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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