Zodef 6mg tab - 6 mg

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Renata Limited

Manufacturer : Renata Limited

Best Price * TK 95.00

* Delivery will be done in Dhaka city only.

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More Information About - Zodef 6mg tab - 6 mg

Description

Generic Name

Deflazacort

Precaution

Adrenal suppression and infection, child, adolescents, elderly, history of TB and steroid myopathy, hypertension, recent MI, CHF, liver failure, renal impairment, DM and glaucoma (including family history), osteoporosis, corneal perforation, severe affective disorders, epilepsy, peptic ulcer, hypothyroidism, pregnancy and lactation.

Indication

Allergic and inflammatory disorders, Duchenne muscular dystrophy

Contra Indication

Systemic infection; live virus vaccines in those receiving immunosuppressive doses.

Dose

N/A

Side Effect

GI disturbances, musculoskeletal, endocrine, neuropsychiatric, ophthalmic, fluid and electrolyte disturbances; susceptible to infection, impaired healing, hypersensitivity, skin atrophy, striae, telangiectasia, acne, myocardial rupture following recent MI, thromboembolism.

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Deflazacort, derived from prednisolone, is a corticosteroid with mainly glucocorticoid activity. An anti-inflammatory dose of 6 mg deflazacort is equiv to 5 mg prednisolone.

Interaction

Antacids, ACE inhibitors, acetazolamide, adrenergic neuron blockers, antidiabetics, aspirin, barbiturate, ?-blockers, calcium-channel blockers, carbamazepine, carbenoxolone, cardiac glycosides, clonidine, coumarins, diazoxide, diuretics, erythromycin, hydralazine, ketoconazole, methotrexate, methyldopa, mifepristone, minoxidil, moxonidine, nitrates, nitroprusside, NSAIDs, oestrogens, phenytoin, primidone, rifamycins, ritonavir, somatropin, ?2 sympathomimetics, theophylline, vaccines.

Pregnancy Category Note

Pregnancy Corticosteroids should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus Infants born to mothers who have received substantial doses of corticosteroids during pregnancy should be carefully observed for signs of hypoadrenalism Lactation Systemically administered corticosteroids appear in human milk and could suppress growth, interfere with endogenous corticosteroid production, or cause other untoward effects Consider the developmental and health benefits of breastfeeding along with the mother?s clinical need for the drug, and any potential adverse effects on the breastfed infant from the drug or from the underlying maternal condition

Adult Dose

Oral Allergic and inflammatory disorders Adult: Usual maintenance 3?18 mg daily (acute disorders, initially up to 120 mg daily). Rheumatoid arthritis: 3-18 mg/day Bronchial asthma: 48-72 mg/day. Duchenne Muscular Dystrophy Indicated for Duchenne muscular dystrophy (DMD) 0.9 mg/kg/day PO qDay Hepatic impairment Mild or moderate: No dose adjustment required Severe: Not studied

Child Dose

Oral Allergic and inflammatory disorders Child 1 month?11 years: 0.25?1.5 mg/kg daily or on alternate days; up to 2.4 mg/kg (max.120 mg) daily in emergency situations. Child 12?17 years: 3?18 mg daily or on alternate days; up to 2.4 mg/kg (max. 120 mg) daily in emergency situations.

Renal Dose

Renal impairment Mild, moderate, or severe: No dose adjustment required

Administration

May take with or without food

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.