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Terbiderm - 250mg
Tablet
Pack Size :
10 Tablet x 1 Strip
Generics :
Terbinafine
Manufacturer :
Orion Pharma Ltd.
Best Price *
TK
500.00
* Delivery will be done in Dhaka city only.
Alternative Product
More Information About - Terbiderm - 250mg
Description
Generic Name
TerbinafinePrecaution
Preexisting liver or renal impairment, pregnancy. Perform liver function tests prior to oral therapy. Lactation: Drug excreted in breast milk; do not useIndication
Tinea pedis, Tinea cruris, Tinea corporis, Dermatophytosis, Nail infectionsContra Indication
Hypersensitivity, active or chronic liver disease, lactation.Dose
N/ASide Effect
>10% Headache (13%) 1-10% Rash (6%),Pruritus (3%),Nausea (3%),Diarrhea (6%),Dyspepsia (4%),Abdominal pain (2%),Taste disturbance (3%),Elevated liver function test results (3%),Visual disturbance (1%) Potentially Fatal: Liver failure, Stevens-Johnson syndrome, neutropaenia.Pregnancy Category
Name : Not Classified
Description
FDA has not yet classified the drug into a specified pregnancy category.Mode of Action
Terbinafine causes fungal cell death by inhibiting squalene epoxidase, the main enzyme in sterol biosynthesis, resulting in ergosterol deficiency within fungal cell walls. It has fungicidal activity against dermatophytes and some yeast.Interaction
Possible increase in levels in drugs metabolised by CYP450 2D6. Decreased terbinafine concentration with rifampicin; increased terbinafine concentration with cimetidine.Pregnancy Category Note
Pregnancy Available data from postmarketing cases in pregnant women are insufficient to evaluate drug-associated risk of major birth defects, miscarriage, or adverse maternal or fetal outcomes Animal data In animal reproduction studies, the drug did not cause malformations or any harm to fetus when administered to pregnant rabbits and rats during period of organogenesis at oral doses up to 12 and 23 times the maximum recommended human dose (MRHD) of 250 mg/day, respectively Because treatment of onychomycosis can be postponed until after pregnancy is completed, it is recommended that oral terbinafine not be initiated during pregnancy Lactation After oral administration, terbinafine is present in human milk; however, there are no data on effects on breastfed child or on milk production; developmental and health benefits of breastfeeding should be considered along with mother?s clinical need for therapy; tablets and any potential adverse effects on breastfed child from therapy or from underlying maternal conditionAdult Dose
Oral Onychomycosis Adult: 250 mg once daily for 6 weeks (fingernail) or 12 weeks (toenail) Tinea Pedis, Tinea Corporis, Tinea Cruris Adult: 250 mg/day PO in single dose or divided q12hr 2-4 wk in tinea cruris, tinea corporis 2-6 wk for tinea pedis Hepatic impairment: Use not recommended in chronic or active liver diseaseChild Dose
Tinea Capitis >4 years (<25 kg): 125 mg/day PO for 6 weeks >4 years (25-35 kg): 187.5 mg/day PO for 6 weeks >4 years (>35 kg): 250 mg/day PO for 6 weeksRenal Dose
Renal impairment: Use not recommended if CrCl <50 mL/minAdministration
May be taken with or without food.Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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