Femastin 15 gm - 0.001

Cream

Pack Size : 1 Tube x 1 Packet

Generics : Estriol

Manufacturer : Square Pharmaceuticals Ltd.

Best Price * TK 1,000.00

* Delivery will be done in Dhaka city only.

Alternative Product

Tablet Ovestin 1 mg Tab Nuvista Pharma Ltd

Tk 10.00

More Information About - Femastin 15 gm - 0.001

Description

Generic Name

Estriol

Precaution

In order to prevent endometrial stimulation, the daily dose should not exceed 8 mg nor should this maximum dose be used for longer than several weeks. As for all hormone replacement therapies, yearly medical examination is advisable. With vaginal infections, a concomitant specific treatment is recommended. Patients with any of the following conditions should be monitored; thrombosis, severe liver disorders; porphyria; a history during pregnancy or previous use of steroids of severe pruritus, cholestatic jaundice, herpes gestationis, or otosclerosis.

Indication

Infertility due to cervical hostility, Menopausal atrophic vaginitis, Menopausal hormone replacement therapy, Dyspareunia, Dryness and itching of vagina due to Oestrogen deficiency, Prevention of recurrent infections of the vagina and lower urinary tract, Micturition complaints (such as frequency and dysuria), Urinary incontinence. Pre- and postoperative therapy in postmenopausal women undergoing vaginal surgery, Climacteric complaints such as hot flushes and night sweating, a diagnostic aid in case of a doubtful atrophic cervical smear.

Contra Indication

? Pregnancy ? Known, past or suspected breast cancer ? Known or suspected oestrogen-dependent malignant tumours (e.g. endometrial cancer) ? Undiagnosed genital bleeding ? Untreated endometrial hyperplasia ? Previous idiopathic or current venous thromboembolism (deep venous thrombosis, pulmonary embolism) ? Active or recent arterial thromboembolic disease (e.g. angina, myocardial infarction) ? Acute liver disease, or a history of liver disease as long as liver function tests failed to return to normal

Dose

N/A

Side Effect

Breast tension or pain, nausea, spotting. Fluid retention, cervical hypersecretion.

Pregnancy Category

Name : X

Description

Studies in animals or humans have demonstrated fetal abnormalities and/or there is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience, and the risks involved in use of the drug in pregnant women clearly outweigh potential benefits.

Mode of Action

Estriol is a naturally occurring oestrogen. It induces normalization of vag epithelium. It is claimed to have only a mild proliferative effect on the endometrium. It only has a short retention time in the nuclei of endometrial cells.

Interaction

Reduced efficacy may occur when used with activated charcoal, barbiturates, carbamazepine, griseofulvin, hydantoin and rifampicin. May possibly change efficacy of oral anticoagulants and increase pharmacologic effects of succinylcholine, theophyllines and troleandromycin.

Pregnancy Category Note

N/A

Adult Dose

Oral Menopausal hormone replacement therapy Adult: 0.5-3 mg daily for 1 mth followed by 0.5-1 mg daily; or 0.25-2 mg daily in combination with other natural oestrogens. A progestogen is required if administered to women with a uterus. Infertility due to cervical hostility Adult: 0.25-1 mg/day on days 6-15 of the menstrual cycle. Increase dose each mth until an optimal effect is obtained. Vaginal Menopausal atrophic vaginitis Adult: As cream: Apply 500 mcg once daily, reduce to twice wkly subsequently.

Child Dose

N/A

Renal Dose

N/A

Administration

Tablet: May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.