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Dexalax - 30mg
Capsule
Pack Size :
10 Capsule x 1 Strip
Generics :
Dexlansoprazole
Manufacturer :
Delta Pharma Ltd
Best Price *
TK
60.00
* Delivery will be done in Dhaka city only.
Alternative Product
More Information About - Dexalax - 30mg
Description
Generic Name
DexlansoprazolePrecaution
Hepatic impairment. Gastric malignancy should be ruled out. Pregnancy and lactation. Lactation Risk Summary There is no information regarding presence of dexlansoprazole in human milk, effects on breastfed infant, or on milk production; however, lansoprazole and its metabolites are present in rat milk; developmental and health benefits of breastfeeding should be considered along with mother?s clinical need for therapy and potential adverse effects on breastfed child from therapy or from the underlying maternal conditionIndication
Oesophagitis, Gastro-oesophageal reflux disease (GERD)Contra Indication
Hypersensitivity.Dose
N/ASide Effect
1-10% Diarrhea (5%),Abdominal pain (4%),Nausea (3%),URI (2-3%),Vomiting (1-2%),Flatulence (1%) <1% (Selected) Arrhythmia,Bradycardia,Barrett's esophagus,DVT,Dyspnea,Hepatomegaly,Hypertension,Paresthesia,Rectal hemorrhage,Vulvovaginal infectionPregnancy Category
Name : Not Classified
Description
FDA has not yet classified the drug into a specified pregnancy category.Mode of Action
R-enantiomer of lansoprazole; PPI; binds to H+/K+-exchanging ATPase (proton pump) in gastric parietal cells, resulting in blockage of acid secretion.Dual release formulation.Interaction
Increased risk of hypomagnesaemia w/ diuretics and digoxin. May decrease plasma concentration of erlotinib, dasatinib and lapatinib. May decrease the bioavailability of itraconazole and ketoconazole. May increase plasma concentration of cilostazol and methotrexate. Reduced bioavailability w/ antacids and sucralfate. Potentially Fatal: May decrease serum levels and pharmacological effects of rilpivirine and atazanavir.Pregnancy Category Note
Pregnancy There are no studies with dexlansoprazole use in pregnant women to inform a drug-associated risk; dexlansoprazole is R-enantiomer of lansoprazole, and published observational studies of lansoprazole use during pregnancy did not demonstrate an association of adverse pregnancy-related outcomes with lansoprazole In animal reproduction studies, oral administration of lansoprazole to rats during organogenesis through lactation at 1.8 times the maximum recommended human dexlansoprazole dose; produced reductions in the offspring in femur weight, femur length, crown-rump length and growth plate thickness (males only) on postnatal day 21; these effects were associated with reduction in body weight gain; advise pregnant women of potential risk to fetus Lactation There is no information regarding presence of dexlansoprazole in human milk, effects on breastfed infant, or on milk production; however, lansoprazole and its metabolites are present in rat milk; developmental and health benefits of breastfeeding should be considered along with mother?s clinical need for therapy and potential adverse effects on breastfed child from therapy or from the underlying maternal conditionAdult Dose
Erosive Esophagitis Capsule: Indicated for healing of all grades of erosive esophagitis (EE) and maintaining healing of EE DR: Indicated for maintaining healing of EE Healing (capsule): 60 mg PO qDay for up to 8 weeks Maintenance (capsule or DR): 30 mg PO qDay for up to 6 months Gastroesophageal Reflux Disease Indicated for treating heartburn associated with symptomatic nonerosive GERD Capsule or DR: 30 mg PO qDay for 4 weeks Hepatic impairment Milde (Child-Pugh A): Dose adjustment not necessary Moderate (Child-Pugh B): Not to exceed 30 mg/day Severe (Child-Pugh C): Not recommendedChild Dose
<12 years Safety and efficacy not established >12 years Erosive Esophagitis Capsule: Indicated for healing of all grades of erosive esophagitis (EE) and maintaining healing of EE DR: Indicated for maintaining healing of EE Healing (capsule): 60 mg PO qDay for up to 8 weeks Maintenance (capsule or DR): 30 mg PO qDay for up to 6 months Gastroesophageal Reflux Disease Indicated for treating heartburn associated with symptomatic nonerosive GERD Capsule or DR: 30 mg PO qDay for 4 weeksRenal Dose
N/AAdministration
Capsule: May take with or without food DR: Take at least 30 minutes before a mealDisclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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