Coversyl - 4mg

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Perindopril Arginine

Manufacturer : Eskayef Pharmaceuticals Ltd.

Best Price * TK 165.00

* Delivery will be done in Dhaka city only.

Alternative Product

Tablet Coversyl - 8mg Eskayef Pharmaceuticals Ltd.

Tk 25.00

Tablet Coversyl Plus - 1.25mg Eskayef Pharmaceuticals Ltd.

Tk 21.00

More Information About - Coversyl - 4mg

Description

Generic Name

Indapamide + Perindopril Erbumine

Precaution

Impaired renal function, risk of hypotension and electrolyte imbalance. Regular monitoring of renal function and plasma levels of potassium are recommended. Blood glucose levels should be monitored in diabetic patients especially in those with low serum potassium levels. Increased risk of neutropenia/agranulocytosis in immunosuppressed patients. Treatment should be discontinued immediately if there is angioneurotic oedema of the face, extremities, lips, tongue, glottis and/or larynx.

Indication

Hypertension

Contra Indication

Hypersensitivity. Severe renal impairment (CrCl <30 ml/min), hypokalaemia, severe hepatic impairment or hepatic encephalopathy, history of angioedema associated with treatment with an ACE inhibitor, children. Dialysis patients or patients with untreated decompensated heart failure. Hereditary/idiopathic angioneurotic oedema. Pregnancy and lactation.

Dose

N/A

Side Effect

Dry cough, headache, bradycardia, dizziness, asthenia, hypokalaemia and orthostatic hypotension. GI effects such as constipation, dry mouth, nausea, epigastric pain, anorexia, abdominal pain and taste disturbance.

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Perindopril is an ACE inhibitor, which acts by inhibiting the conversion of angiotensin I to angiotensin II, reducing the activity of the sympathetic nervous system and inhibiting enzyme kininase, which is involved in the conversion of bradykinin and other substances. Indapamide is a sulfonamide derivative with an indole ring. It inhibits the reabsorption of sodium in the cortical dilution segment, thus increasing urinary output, resulting in an antihypertensive effect.

Interaction

Additive effect with other antihypertensive agents and diuretics. Increased chance of hypokalaemia with corticosteroids, corticotropin and amphotericin. Potentially Fatal: Increased risk of lithium toxicity. Hypokalaemia enhances digitalis toxicity with cardiac gycosides.

Pregnancy Category Note

N/A

Adult Dose

Oral Hypertension Adult: 1 tab once daily in the morning.

Child Dose

N/A

Renal Dose

Renal impairment: CrCl (ml/min) Dosage Recommendation <30 Avoid use. 30-60 Dose adjustment may be needed

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.