Ticoma B - 5ml

Drops
Pack Size :   1 Bottle x 1 Packet
Manufacturer :   Opsonin Pharma Ltd.
Best Price * TK  110.42
* Delivery will be done in Dhaka city only.

More Information About - Ticoma B - 5ml

Description

Generic Name

Brimonidine Tartrate 0.2% + Timolol Maleate 0.5% Eye prep

Precaution

Patients wearing soft contact lenses should wait for at least 15 min after instilling brimonidine tartrate before inserting soft contact lenses. Renal or hepatic impairment. CV disease. Use with caution in patients with depression, cerebral or coronary insufficiency, Raynaud's phenomenon, orthostatic hypotension or thromboangitis obliterans. Pregnancy, lactation. Lactation: use caution

Indication

Open-angle glaucoma, Ocular hypertension

Contra Indication

Hypersensitivity. Patients receiving MAO inhibitor therapy.

Dose

N/A

Side Effect

5-15% Allergic conjunctivitis,Conjunctival folliculosis,Conjunctival hyperemia,Eye pruritus,Ocular burning,Stinging 1-5% Asthenia,Blepharitis,Corneal erosion,Depression,Epiphora,Eye discharge,Eye dryness,Eye irritation,Eye pain,Eyelid edema,Eyelid erythema,Eyelid pruritus,Foreign body sensation,Headache,Hypertension,Oral dryness,Somnolence,Superficial punctate keratitis,Visual disturbance

Pregnancy Category

Name : C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Brimonidine is an alpha 2-adrenoceptor agonist which works to reduce aqueous humor production and increase uveoscleral flow. Timolol is a non-selective beta-adrenergic receptor blocker. It does not have significant intrinsic sympathomimetic activity, direct myocardial depressant activity or local anaesth activity. Exact mechanism of ocular hypotensive effect is unclear, but it is thought to be related to reduction of aqueous humour formation. beta-blockade also causes lowering of BP.

Interaction

Brimonidine Tartrate: Possibility of an additive or potentiating effect with CNS depressants e.g. alcohol, barbiturates, opiates, sedatives or anaesthetics. Caution when used with ?-blockers (ophthalmic and systemic), antihypertensives or cardiac glycosides. TCAs can affect the metabolism and uptake of circulating amines. Timolol: Concomitant admin w/ reserpine may increase hypotension and bradycardia. Additive effects w/ other antihypertensives (e.g. hydralazine, methyldopa). Increased ?-adrenergic blockade (e.g. decreased heart rate) w/ quinidine. Rebound HTN due to abrupt withdrawal of clonidine. Hypotensive effect may be antagonised by NSAIDs (e.g. indomethacin, ibuprofen).

Pregnancy Category Note

Pregnancy Category: C Lactation: use caution

Adult Dose

Adult: Ophth: Instill 1 drop 2 times/day approximately 12 hours apart.

Child Dose

N/A

Renal Dose

N/A

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.

Others Product

In Stock
Prescribed
Others Alcohol Pads Box - 100pis Antiseptic Delta Pharma Ltd
Tk 200
In Stock
Tablet Glymin 500 mg Tab Metformin Hydrochloride Healthcare Pharmaceuticals Ltd.
Tk 30
In Stock
Drops Xylocon - 0.0003 Oxymetazoline Hydrochloride .025 % Nasal prep Square Pharmaceuticals Ltd.
Tk 40.13
In Stock
Tablet Bigmet 500 mg Tab Glipizide + Metformin Hydrochloride Renata Limited
Tk 40