Lotepro G 5ml Eye Drops - 500mg

Drops

Pack Size : 1 Bottle x 1 Packet

Generics : Loteprednol Etabonate + Gatifloxacin

Manufacturer : Incepta Pharmaceuticals Ltd.

Best Price * TK 250.00

* Delivery will be done in Dhaka city only.

Alternative Product

Drops Loteflam g 500/100 gm Eye Oint. - 300 mg General Pharmaceuticals Ltd.

Tk 250.00

More Information About - Lotepro G 5ml Eye Drops - 500mg

Description

Generic Name

Loteprednol + Gatifloxacin eye prep

Precaution

General: Patients should be advised not to wear contact lenses if they have signs and symptoms of bacterial conjunctivitis. Fungal infections of the cornea are particularly prone to develop coincidentally with long term local steroid application. Patients with bleeding tendencies: This fixed dose combination should be used with care in patients with known bleeding tendencies, or in patients who are receiving other medications which may prolong bleeding time. Ability to drive: As this fixed dose combination may cause transient blurring on instillation, the use of hazardous machinery or driving is not recommended unless vision is clear.

Indication

Post-operative inflammatory conditions of the eye

Contra Indication

Loteprednol and Gatifloxacin as with other ophthalmic corticosteroids, is contraindicated in most viral diseases of the cornea and conjunctiva including epithelial herpes simpiex and also in mycobacterial infection of the eye and fungal diseases of ocular structures. It is also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids. It is also contraindicated in patients with a history of hypersensitivity to other quinlones, acetylsalicylic acid and other nonsteroidal anti-inflammatory medicines.

Dose

Apply one or two drops of this suspension into the conjunctival sac of the affected eye(s) every four to six hours. During the initial 24 to 48 hours, the dosing may be increased, to every one to two hours. Frequency should be decreased gradually as warranted by improvement in clinical signs. Care should be taken not to discontinue therapy prematurely.

Side Effect

The adverse events reported with the fixed dose combination were irritation, pain, redness, photophobia, stinging, itching, discharge & blurred vision. Redness was the most commonly observed adverse event occurring in 6% of patients. Itching, discharge, photophobia & blurred vision were seen in less than 2% cases.

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Loteprednol etabonate is an ester based corticosteroid which controls the formation of prostaglandin and leukotrienes and reduces ocular inflammation. The antibacterial action of Gatifloxacin results from inhibition of DNA gyrase and topoisomerase IV. DNA gyrase is an essential enzyme that is involved in the replication, transcription and repair of bacterial DNA. Topoisomerase IV is an enzyme known to play a key role in the partitioning of the chromosomal DNA during bacterial cell division.

Interaction

N/A

Pregnancy Category Note

N/A

Adult Dose

Ophthalmic Adult Apply one or two drops of this suspension into the conjunctival sac of the affected eye(s) every four to six hours. During the initial 24 to 48 hours, the dosing may be increased, to every one to two hours. Frequency should be decreased gradually as warranted by improvement in clinical signs. Care should be taken not to discontinue therapy prematurely.

Child Dose

N/A

Renal Dose

N/A

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.