Pires-M - 100 ml

Syrup

Pack Size : 1 Bottle x 1 Packet

Generics : Guaifenesin + Levomenthol + Diphenhydramine

Manufacturer : Navana Pharmaceuticals Ltd.

Best Price * TK 80.00

* Delivery will be done in Dhaka city only.

Alternative Product

Syrup Tuscof 100 ml Syp. - 100 ml Eskayef Pharmaceuticals Ltd.

Tk 85.00

More Information About - Pires-M - 100 ml

Description

Generic Name

Guaiphenesin + Diphenhydramine + Levomenthol

Precaution

This product should be not used for persistent or chronic cough, such as occurs with asthma, or where cough is accompanied by excessive secretion. May impair ability to drive or operate machinery. Should be used with caution in patients with narrow-angle glaucoma or symptomatic prostatic hypertrophy. Avoid alcohol.

Indication

Relief of cough with associated congestive symptoms

Contra Indication

Known hypersensitivity to the product or any of its constituents. Not to be used in children under the age of 12 years.

Dose

N/A

Side Effect

Diphenhydramine may cause drowsiness, dizziness, gastrointestinal disturbance; dry mouth nose and throat; difficulty in urination or blurred vision. Less frequently it may cause palpitations, tremor, convulsions or paraesthesia. Hypersensitivity reactions have been reported, in particular, skin rashes, erythema, urticaria and angiodema. Gastro-intestinal discomfort, nausea and vomiting have occasionally been reported with guaifenesin particularly in large doses. Adverse reactions to levomenthol at the low concentration present are not anticipated.

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Diphenhydramine is a potent antihistamine and antitussive with anticholinergic and sedative properties. Recent experiments have shown that the antitussive action is discrete from H1-receptor blockade and is located in the brain stem. Guaifenesin is reported to reduce the viscosity of tenacious sputum and is used as an expectorant. Levomenthol has mild local anaesthetic and decongestant properties.

Interaction

This product contains diphenhydramine and therefore may potentiate the effects of alcohol, codeine, antihistamines and other CNS depressants. As diphenhydramine possesses some anticholinergic activity, the effects of anticholinergics (e.g. some psychotropic drugs and atropine) may be potentiated by this product. This may result in tachycardia, dry mouth, gastrointestinal disturbances (e.g. colic), urinary retention and headache.

Pregnancy Category Note

N/A

Adult Dose

Adults: Syrup 2 tsf 4 times a day. For night time cough relief 2 tsf at bedtime followed by 2 tsf every 6 hours. Hepatic dysfunction Subjects with moderate to severe hepatic dysfunction should exercise caution when using this product

Child Dose

Children>12 years and over: Syrup 2 tsf 4 times a day. For night time cough relief 2 tsf at bedtime followed by 2 tsf every 6 hours. Children<12 years: Safety & Efficacy not established

Renal Dose

Subjects with moderate to severe renal dysfunction should exercise caution when using this product

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.