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reelife -
Tablet
Pack Size :
14 Tablet x 1 Strip
Generics :
Amitriptyline + Chlordiazepoxide
Manufacturer :
Eskayef Pharmaceuticals Ltd.
Best Price *
TK
112.00
* Delivery will be done in Dhaka city only.
More Information About - reelife -
Description
Generic Name
Amitriptyline + ChlordiazepoxidePrecaution
Children and Antidepressants Antidepressants increased the risk of suicidal thinking and behavior in children, adolescents, and young adults (age <24 yr) taking antidepressants for major depressive disorders and other psychiatric illnesses. Caution in BPH, urinary/GI retention, increased IOP, thyroid dysfunction, open-angle glaucoma, seizure disorders, brain tumor, respiratory impairment, respiratory disease. Risk of anticholinergic side-effects. May cause orthostatic hypotension. Paradoxical reactions including hyperactive or aggressive behavior reported. Both agents may cause sedation and impair ability to perform tasks requiring mental alertness Patients should be monitored closely for changes in behavior, clinical worsening, and suicidal tendencies; monitor during the initial 1-2 months of therapy and dosage adjustments. Not approved for treatment of dementia-related psychosis. Lactation: Excretion in milk unknown; not recommendedIndication
Depression with Anxiety, agitation or tension.Contra Indication
Hypersensitivity. Severe cardiovascular disorders, Angle clossure glaucoma, Within 14 days of MAOIs, Any drugs or conditions that prolong QT interval, Acute recovery post-MI.Dose
N/ASide Effect
Drowsiness, Dry mouth, Constipation, Blurred vision, Dizziness, Bloating, Vivid dreams, Impotence, Tremor, Confusion, Nasal congestion, Edema, Syncope, Ataxia, EEG abnormalities, Menstrual irregularities, Blood dyscrasias (agranulocytosis), Hepatic dysfunction (jaundice).Pregnancy Category
Name : D
Description
There is positive evidence of human fetal risk based on adverse reaction data from investigational or marketing experience or studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.Mode of Action
Chlordiazepoxide: Antianxiety agent; depresses all levels of CNS, including limbic and reticular formation, possibly by increasing gamma-aminobutyric acid (GABA) activity, a major inhibitory neurotransmitter. Amitriptyline: Antidepressant; neurotransmitter (especially norepinephrine and serotonin) reuptake inhibitor; elicits anticholinergic effects.Interaction
N/APregnancy Category Note
Pregnancy Category: D Lactation: Excretion in milk unknown; not recommendedAdult Dose
Depression with Anxiety 1 tablet (5-10 mg chlordiazepoxide/12.5-25 mg amitriptyline) PO three/four times daily; may increase to 6 tablets if necessary; 2 tablets reported to be effective in some patients. Elderly: Avoid; strong anticholinergic and sedative effects; may cause orthostatic hypotension (Beers criteria) Consider alternatives; if must use, initiate with lower initial dose; long-acting active metabolites 1 tablet (5 mg/12.5 mg) PO three times dailyChild Dose
N/ARenal Dose
N/AAdministration
N/ADisclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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