Norix 1 - 1.5mg

Tablet

Pack Size : 1 Strip x 1 Box

Generics : Cilnidipine

Manufacturer : SMC Enterprise Limited Bangladesh

Best Price * TK 60.00

* Delivery will be done in Dhaka city only.

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More Information About - Norix 1 - 1.5mg

Description

Generic Name

Levonorgestrel

Precaution

Sex-steroid dependent cancer, past ectopic pregnancy, malabsorption syndromes, functional ovarian cysts, active liver disease, recurrent cholestatic jaundice, history of jaundice in pregnancy, CV or renal impairment, DM, asthma, epilepsy, migraine, conditions aggravated by fluid retention, depression and thromboembolism (high doses); lactation.

Indication

Contraception, Emergency contraception, Menopausal hormone replacement therapy, Menorrhagia,

Contra Indication

Pregnancy, undiagnosed vaginal bleeding, severe arterial disease; liver adenoma, porphyria; after recent evacuation of hydatidiform mole; history of breast cancer; hepatic impairment.

Dose

N/A

Side Effect

>10% Headache (12%),Acne (15%),Ovarian cysts (13%),Enlarged follicles (12%),Amenorrhea (1-12%),Abdominal pain (12%),Uterine/vaginal bleeding alterations (52%),Intermenstrual bleeding/spotting (23%),Vulvovaginitis (20%),Ectopic pregnancy (?50%) 1-10% Depression (4%),Migraine (2%),Alopecia (1%),Dysmenorrhea (9%),Menorrhagia (6%),Breast tenderness (3-9%),Pelvic pain (6%),Leukorrhea (5%),Vaginal discharge (4%),Pelvic infection (1%) <1% Angioedema,Cervical perforation,Failed insertion,Sepsis,Uterine bleeding,Device breakage Potentially Fatal: Thrombocytopenia, stroke.

Pregnancy Category

Name : Not Classified

Description

FDA has not yet classified the drug into a specified pregnancy category.

Mode of Action

Levonorgestrel, a nortestosterone derivative, is an active isomer of norgestrel. It is a potent inhibitor of ovulation and has androgenic activity.

Interaction

Reduced efficacy with enzyme-inducing drugs; aminoglutethimide. May inhibit ciclosporin metabolism.

Pregnancy Category Note

Pregnancy Use of is contraindicated in pregnancy or with a suspected pregnancy because there is no need for pregnancy prevention in a woman who is already pregnant and therapy may cause adverse pregnancy outcomes; if a woman becomes pregnant likelihood of ectopic pregnancy is increased and there is increased risk of miscarriage, sepsis, premature labor, and premature delivery; remove product if possible, if pregnancy occurs in a woman; if product cannot be removed, follow pregnancy closely Studies report no adverse effects on fetal and infant development associated with long-term use of contraceptive doses of oral progestins in a pregnant woman; however, there have been reported cases of masculinization of external genitalia of female fetus following exposure to progestins at doses greater than those currently used for oral contraception; animal reproduction studies not conducted Lactation Published studies report presence of LNG in human milk; small amounts of progestins (approximately 0.1% of total maternal doses) were detected in breast milk of nursing mothers who used other LNG-releasing IUSs, resulting in exposure of LNG to the breastfed infants; there are no reports of adverse effects in breastfed infants with maternal use of progestin-only contraceptives; isolated cases of decreased milk production reported with a LNG-releasing IUS; developmental and health benefits of breastfeeding should be considered along with mother?s clinical need for therapy and any potential adverse effects on breastfed child therapy or from underlying maternal condition

Adult Dose

Oral Emergency contraception Adult: 1.5 mg as soon as possible or within 72 hr of coitus. Alternatively, 750 mcg as soon as possible or within 72 hr of coitus followed by a 2nd dose 12 hr later. Most effective if taken as soon as possible after unprotected intercourse Menopausal hormone replacement therapy Adult: As progestogenic component: 75-250 mcg for 10-12 days of a 28-day cycle. Contraception Adult: Monotherapy: 30 or 37.5 mcg daily.

Child Dose

N/A

Renal Dose

N/A

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.