Indication:

Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders

Pharmacology:

Cinnarizine is a peripheral antivasoconstrictor, antihistamine, and labyrinthine sedative. Cinnarizine is a calcium antagonist that inhibits the intracellular inflow of Ca2+. By reducing Ca2+ influx through smooth muscle calcium channels, it reduces Ca2+-dependent contraction of arterial smooth muscle, improving vestibular symptoms and preventing peripheral arterial disease.

Dosage (breakdown or, not) :

• Usual adult dose: 15 to 30 mg three times daily.
• Children (5 to 12 years): Half of the adult dose.
• Motion sickness: A dose of 30 mg two hours before the start of the journey and 15 mg every 8 hours during the journey.
• Peripheral arterial diseases: 75 mg two or three times daily.

Administration:

Should be taken with food.

Interaction

Cinnarizine has not been found to interact with antihypertensives, diuretics, anticoagulants, or hypoglycaemics when taken together.

Contraindications

There are no known contraindications to using this product. It has been discovered to drastically lower blood pressure. In hypotensive patients, however, the medication should be administered with caution.

Side Effects:

Side effects such as drowsiness and gastrointestinal problems are relatively uncommon. They are temporary and can be easily avoided by progressively obtaining the correct dosage. Rarely, allergic skin reactions and exhaustion have been recorded. Extrapyramidal symptoms may worsen or occur in older patients who are on long-term treatment. In such circumstances, the treatment should be lowered or discontinued.

Pregnancy:

Cinnarizine's safety in human pregnancy has not been confirmed, despite the absence of teratogenic effects in animal investigations. As a result, it is not recommended to use Cinnarizine during pregnancy.

Precautions & Warnings

Cinnarizine can make you drowsy, so don't drive or operate machinery if you're impacted. Avoid consuming alcoholic beverages.

Storage Conditions

Keep the temperature below 30°C and away from light and moisture. Keep out of children's reach.