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Virux 70ml 200mg/5ml
Suspension
Pack Size :
1 Bottle x 1 Packet
Generics :
Acyclovir
Manufacturer :
Square Pharmaceuticals Ltd.
Best Price *
TK
125.85
* Delivery will be done in Dhaka city only.
Alternative Product
More Information About - Virux 70ml 200mg/5ml
Description
Generic Name
AcyclovirPrecaution
Renal impairment. Pregnancy, lactation. Neurological abnormalities with significant hypoxia, serious hepatic or electrolyte abnormalities. Maintain adequate hydration. Lactation: Drug enters breast milk; use with caution.Indication
Herpes simplex infections, Varicella zoster (chickenpox), Herpes zoster (shingles), Genital herpesContra Indication
Hypersensitivity.Dose
N/ASide Effect
>10% Oral Malaise (<12%) 1-10% Parenteral Inflammation or phlebitis at injection site (9%),Nausea (7%),Vomiting (7%),Rash or hives (2%),Elevated transaminase levels (1-2%) Oral Nausea (2-5%),Vomiting (<3%),Diarrhea (2-3%),Headache (2%) <1% Abdominal pain,Aggression/confusion,Agitation,Alopecia,Anaphylaxis,Anemia,Angioedema,Anorexia,Ataxia,Coma,Disseminated intravascular coagulation (DIC),Dizziness,Fatigue Potentially Fatal: Occasionally neurotoxicity after IV use: Lethargy, confusion, agitation, tremors, seizures, coma.Pregnancy Category
Name : B
Description
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.Mode of Action
Activity against HSV types I and II and varicella-zoster virus is due to intracellular conversion of aciclovir to the monophosphate by viral thymidine kinase with subsequent conversion to the diphosphate and active triphosphate by cellular enzymes. This active form inhibits viral DNA synthesis and replication by interfering with viral DNA polymerase enzyme and being incorporated into viral DNA.Interaction
Probenecid, cimetidine and mycophenolate mofetil may increase the plasma concentration of aciclovir. Increased nephrotoxic effects w/ drugs that affect renal physiology (e.g. ciclosporin, tacrolimus).Pregnancy Category Note
Pregnancy category: B Lactation: Drug enters breast milk; use with cautionAdult Dose
Oral Primary herpes simplex infections Adult: 200 mg 5 times daily every 4 hr for 5-10 days; for severely immuno compromised patients and those with impaired absorption: 400 mg 5 times daily for 5 days. Suppression of recurrent herpes simplex Adult: 800 mg daily in 2-4 divided doses. May reduce to 400-600 mg daily if necessary. Reassess the condition every 6-12 mth. For mild or infrequent recurrences: Episodic treatment may be used: 200 mg 5 times daily for 5 days, preferably begun during the prodromal period. Prophylaxis of herpes simplex in immunocompromised patients Adult: 200-400 mg 4 times daily. Varicella zoster 800 mg 5 times/day for 5-7 days. Herpes zoster 800 mg 5 times/day for 7-10 days.Child Dose
Child: PO 900 mg/m2/day q8h 60?80 mg/kg/day (max 4 g/day) q6?8h Varicella Zoster (Chickenpox) >2 years and <40 kg: 20 mg/kg/dose PO q6hr for 5 days; not to exceed 800 mg/dose >10 mL/min/1.73 m?: 200 mg q4hr (five times daily) 400 mg every 12 hr 0-10 mL/min/1.73 m?: 200 mg q12hr >10 mL/min/1.73 m?: 400 mg q12hr 800 mg every 4 hr 0-10 mL/min/1.73 m?: 800 mg q12hr 10-25 mL/min/1.73 m?: 800 mg q8hr >25 mL/min/1.73 m?: 800 mg q4hr (five times daily)Renal Dose
N/AAdministration
May be taken with or without food. May be taken w/ meals to reduce GI discomfort. Reconstitution: Add 10 mL or 20 mL of sterile water for inj to a vial labeled as containing 500 mg or 1,000 mg of aciclovir, respectively, to provide a soln containing 50 mg/mL. The appropriate dose of reconstituted soln should then be withdrawn from the vial and diluted w/ 50-125 mL of a compatible IV infusion soln.Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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