Indications:
Filin 100 mg Tablet is suitable for the treatment and prevention of bronchospasm associated with asthma, emphysema and chronic bronchitis. It is also suitable for the treatment of adult cardiac and left ventricular asthma or congestive heart failure.

Pharmacology:
Chronic bronchospasm:

Dosage (breakdown or, not) :

Adult: 
As hydrate: Initially, 225-450 mg bid, increased if necessary.

Child: 
3 yr: As modified-release hydrate: 12 mg/kg daily increased to 24 mg/kg daily in 2 divided doses after 1 wk.

Administration:
Other xanthines. Clearance reduced by allopurinol, some antiarrhythmics, cimetidine, disulfiram, fluvoxamine, interferon-alpha, macrolide antibiotics, quinolones, oral contraceptives, thiabendazole and viloxazine. Clearance increased by phenytoin, anticonvulsants, ritonavir, rifampicin, sulfinpyrazone, cigarette smoking. Corticosteroids, diuretics, beta2-agonists. Potentially Fatal: Increased risk of cardiac arrhythmias with sympathomimetics and halothane. Tachycardia with pancuronium. beta-blockers inhibit metabolism. Increased risk of convulsion with quinolones, ketamine.

Interaction:
Hypersensitivity.

Contraindication: 
Filin 100 mg Tablet should not be used in patients allergic to xanthine or ethylenediamine. Active peptic ulcer patients should not take it because it can increase the volume and acidity of gastric secretions.

Side Effects: 
The most common adverse reactions are stomach irritation, nausea, vomiting, diarrhea, hematemesis, epigastric pain, and tremor. These are usually the first signs of intoxication, however, at high doses, ventricular arrhythmias or seizures can be the first signs and peptic ulcers, headaches, irritability, irritability, insomnia, seizures, convulsions and hyperexcitability Reflex, palpitations, tachycardia, hypotension, circulatory failure, ventricular arrhythmia, flushing, proteinuria, diuresis, and hematuria. Inappropriate ADH syndrome can also occur.

Pregnancy: 
The use of Filin 100 mg Tablet in pregnant women must be balanced with the risk of uncontrolled diseases.

Precautions & Warnings: 
Patients with peptic ulcer, hyperthyroidism, high blood pressure, arrhythmia or other cardiovascular diseases or epilepsy should use aminophylline with caution, as these conditions may aggravate. Heart failure, liver dysfunction, chronic alcoholism, acute febrile illness, newborns and the elderly should also be used with caution, because in all these cases, theophylline clearance rate may be reduced, resulting in serum concentrations of theophylline and theophylline Elevated. Serum half-life.

Storage Conditions:
Store at or below 30°C in a dry, dark area. Keep out of children's reach.