Avoid contact with eyes and mucous membranes. May damage latex contraceptives.
During pregnancy: There is no information of any abnormality or adverse event in neonates while Econazole Cream / VT had been used during pregnancy.
During lactation: As the systemic absorption of Econazole Nitrate cream is extremely low after topical/vaginal use, excretion in breastmilk is likely to be negligible. So, it can be used topically/vaginally during lactation if needed.
Indication
Vaginal thrush, Vulvo-vaginal candidiasis, Fungal infection of vagina.
Contra Indication
Hypersensitivity. Porphyria;
Dose
N/A
Side Effect
Vulvar/vaginal burning; erythema; itching;
Pregnancy Category
Name :
C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Econazole modifies the permeability of cell wall membrane in fungi; may interfere w/ RNA and protein synthesis, and lipid metabolism.
Interaction
Theoretical potential for compd metabolized by CYP3A4/2C9, oral anticoagulants eg warfarin & acenocoumarol.
Pregnancy Category Note
N/A
Adult Dose
Vag candidiasis As VT: 150 mg/day at bedtime for 3 consecutive nights.
Vaginal infection As Vaginal cream: Applied with the applicator par vaginally once or twice daily.
Child Dose
N/A
Renal Dose
N/A
Administration
N/A
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