Cinarzin Plus - 20 mg

Tablet
Pack Size :   10 Tablet x 1 Strip
Best Price * TK  20.00
* Delivery will be done in Dhaka city only.

More Information About - Cinarzin Plus - 20 mg

Description

Generic Name

Cinnarizine + Dimenhydrinate

Precaution

Hypotension; pregnancy; lactation; elderly. May impair ability to drive or operate machineries.

Indication

Nausea and vomiting, motion sickness, vertigo, meniere's disease, peripheral vascular diseases, cerebrovascular disorders, vestibular disorders

Contra Indication

Proven hypersensitivity to the drug. Parkinson's disease. Childn and neonates.

Dose

N/A

Side Effect

Extrapyramidal symptoms sometimes associated with severe depression. Drowsiness, headache, GI upsets, unsteadiness, headache; rarely skin and hypersensitivity reactions, dry mouth, blurred vision, urinary difficulty or retention, constipation and increased gastric reflux, fatigue. Hypolipidaemic effect.

Pregnancy Category

Name : C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Cinnarizine has calcium-channel blocking activity selective for arterial smooth muscle. It also has some antihistamine activity. Cinnarizine acts as a labyrinthine sedative. It also improves microcirculation by reducing ischaemia-induced blood viscosity. Dimenhydrinate is an antihistamine which also has antimuscarinic and central sedative action. It also exerts a depressant action on hyperstimulated labyrinthine function.

Interaction

Cinnarizine: CNS depressant effect enhanced with alcohol. Action potentiated by domperidone. Dimenhydrinate: Physically incompatible with aminophylline, hydrocortisone, phenothiazines and some barbiturates in solution. Potentially Fatal: Potentiates the sedative effects of CNS depressants including alcohol, barbiturates, opioid analgesics, sedatives and neuroleptics. MAOIs, atropine, TCAs enhance antimuscarinic effect. Masks ototoxicity produced by aminoglycoside antibiotics.

Pregnancy Category Note

N/A

Adult Dose

Oral Peripheral vascular disease Adult: 75 mg bid or tid. Motion sickness Adult: 30 mg 2 hr before travel then 15 mg 8 hrly during the journey if necessary. Cerebrovascular disorders Adult: 75 mg once daily. Vertigo and vestibular disorders Adult: 30 mg tid or 75 mg 1-2 times daily.

Child Dose

Oral Motion sickness Child: 5-12 yr 15 mg 2 hr before travel then 7.5 mg 8 hrly during the journey as necessary. Vertigo and vestibular disorders Child: 5-12 yr 15 mg tid.

Renal Dose

N/A

Administration

Should be taken with food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.

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