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More Information About - Cefditor 200mg tab - 200 MG
Description
Generic Name
CefditorenPrecaution
Pregnancy and lactation. Patients with penicillin allergy. Avoid prolonged use as pivalate-containing compounds may cause carnitine deficiency over time; greater risk of carnitine deficiency in patients with renal impairment or decreased muscle mass. May decrease prothrombin activity especially in patients with renal or hepatic impairment, poor nutritional status, prolonged antibiotic treatment or patients previously stabilised on anticoagulant therapy. Long term use may result in development of drug-resistant bacteria, or superinfection including Clostridium difficile-associated diarrhoea and pseudomembranous colitis. Lactation: excretion in milk unknown; use with cautionIndication
Pharyngitis, Community-acquired pneumonia, Susceptible infections, Tonsillitis, Soft tissue infections, Respiratory tract infections, Acute Exacerbations of Chronic bronchitisContra Indication
Hypersensitivity to Cefditoren, other cephalosporins; or milk proteins. Carnitine deficiency.Dose
N/ASide Effect
>10% Diarrhea (11-15%) 1-10% Nausea (4-6%),Headache (2-3%),Abdominal pain (2%),Dyspepsia (1-2%),Vomiting (1%) <1% Bacterial/fungal superinfection,C. difficile colitis,Hypersensitivity,Increased bleeding time,Stevens-Johnson syndrome,Vaginal moniliasis Potentially Fatal: Hypersensitivity, anaphylaxis, Stevens-Johnson syndrome, toxic epidermal necrolysis.Pregnancy Category
Name : B
Description
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.Mode of Action
Cefditoren is a third generation cephalosporin used for treatment of susceptible infections caused by gram-positive and gram-negative bacteria. It inhibits bacterial cell wall synthesis by binding to one or more of the penicillin-binding proteins (PBPs).Interaction
Reduced oral bioavailability when coadministered with antacids or H2-receptor antagonists. Probenecid may increase plasma concentration and prolong half-life of Cefditoren. May enhance anticoagulant effect of vitamin K antagonists (e.g. warfarin).Pregnancy Category Note
Pregnancy Category: B Lactation: excretion in milk unknown; use with cautionAdult Dose
Oral Community-acquired pneumonia Adult: 400 mg bid for 14 days. Acute bacterial exacerbation of chronic bronchitis Adult: 400 mg bid for 10 days. Pharyngitis ; Tonsillitis; Uncomplicated skin and skin structure infections Adult: 200 mg bid for 10 days.Child Dose
<12 years old: Safety & efficacy not established >12 years old: As in adultsRenal Dose
Renal impairment: CrCl (ml/min) 30-49 Maximum: 200 mg bid <30 Maximum: 200 mg once dailyAdministration
Should be taken with food.Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.
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