Antrenex - 5mg

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Oxyphenonium Bromide

Manufacturer : Opsonin Pharma Ltd.

Best Price * TK 12.50

* Delivery will be done in Dhaka city only.

Alternative Product

Tablet A Spasm 5mg Acme Laboratories Ltd.

Tk 108.00

More Information About - Antrenex - 5mg

Description

Generic Name

Oxyphenonium Bromide

Precaution

Children; elderly; benign prostatic hyperplasia; acute MI, cardiac failure, hypertension, thyrotoxicosis; pregnancy and lactation; fever; angle-closure glaucoma.

Indication

Peptic ulcer, Gastrointestinal tract spasm, Visceral spasms

Contra Indication

Urinary outflow obstruction, paralytic ileus, myasthenia gravis.

Dose

N/A

Side Effect

Dryness of mouth, difficulty in talking/swallowing; reduced bronchial secretions; blurring of vision, photophobia; bradycardia followed by tachycardia and arrhythmias; urinary retention, constipation, vomiting, nausea; confusion and giddiness. Potentially Fatal: Arrhythmias (especially after MI).

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Oxyphenonium is an anticholinergic drug. It exerts its action by inhibiting muscarinic (cholinergic) receptors on smooth muscles, cardiac muscles and prevents the effect of Acetylcholine. Inhibition of Acetylcholine produces relaxation of smooth muscles and prevents the muscle spasm in irritable bowel syndrome. Oxyphenonium also has a direct relaxant effect on smooth muscle. It also inhibits gastrointestinal propulsive movement and decreases gastric acid secretion and control bronchial, pharyngeal and tracheal secretions. It also possesses nicotinic blocking activity and interferes with ganglionic or neuromuscular transmission. It cross the BBB poorly and does not produce CNS effect.

Interaction

Reduced gastric motility interferes with absorption of other drugs. Effects potentiated by other antimuscarinics including amantadine, some antihistamines, phenothiazines and TCA.

Pregnancy Category Note

N/A

Adult Dose

Adults: 1-2 tablets 3-4 times daily.

Child Dose

Children: 1/2-1 tablet 1-3 times daily.

Renal Dose

N/A

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.