Almex 10 ml

Suspension
Pack Size :   1 Bottle x 1 Packet
Generics :   Albendazole
Best Price * TK  20.00
* Delivery will be done in Dhaka city only.

More Information About - Almex 10 ml

Description

Generic Name

Albendazole

Precaution

Monitor blood counts and liver function. Administer within 7 days of start of normal menstruation in women of childbearing age. Adequate nonhormonal contraceptive measures must be taken during and for 1 mth after therapy. Perform liver function tests and blood counts before and every 2 wk during high dose therapy of hydatid disease. Lactation: unknown, use caution.

Indication

Helminthiasis, Echinococcosis, Neurocysticercosis, Enterobiasis, Ascariasis, Hookworm infections, Strongyloidiasis, Giardiasis, Filariasis

Contra Indication

Pregnancy and lactation. Neonates. Hypersensitivity, liver impairment.

Dose

N/A

Side Effect

>10% Headache,Neurocysticercosis (11%),Hydatid disease (1.3%),Abnormal LFT,Hydatid disease (15.6%),Neurocysticercosis (<1%) 1-10% Abdominal pain,Hydatid disease (6%),Nausea/vomiting,Hydatid disease (3.7%),Neurocysticercosis (6.2%),Dizziness/vertigo,Hydatid disease (1.2%),Neurocysticercosis (<1%),Increased intracranial pressure,Neurocysticercosis (1%),Meningeal signs,Neurocysticercosis (1%),Alopecia (reversible),Hydatid disease (1.6%),Neurocysticercosis (<1%),Fever,Hydatid disease (1%) <1% (selected) Rash,Urticaria,Agranulocytosis,Aplastic anemia,Bone marrow suppression,Granulocytopenia,Pancytopenia,Thrombocytopenia,Hepatitis,Acute liver failure,Acute renal failure Potentially Fatal: Bone marrow depression.

Pregnancy Category

Name : C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Albendazole sulfoxide (active metabolite), causes selective degeneration of cytoplasmic microtubules in intestinal and tegmental cells of intestinal helminths and larvae; glycogen is depleted, glucose uptake and cholinesterase secretion are impaired and desecratory substances accumulate intracellulary. ATP production decreases, causing energy depletion, immobilisation and worm death.

Interaction

Increased serum concentrations w/ dexamethasone, praziquantel and cimetidine. Decreased serum concentrations w/ aminoquinoline (antimalarials), carbamazepine, phenobarbital, and phenytoin.

Pregnancy Category Note

Pregnancy Category: C Lactation: unknown, use caution

Adult Dose

Oral Ancylostoma, Ascariasis, Hookworm, Trichostrongylus, Enterobius (Pinworm) 400 mg PO once as a single dose Tapeworm infections Adult: 400 mg daily on an empty stomach for 3 consecutive days. Max: 400 mg daily; 1200 mg for 3 days. If patient is not cured after 3 weeks, a second course of treatment is needed. In cases of Hymenolepis nana infestations, retreatment in 10-21 days is recommended. Strogyloidiasis or taeniasis - 400 mg once daily for three consecutive days. Giardiasis - 400 mg once daily for five days. Hydatid disease (Echinococcosis) Adult: <60 kg: 15 mg/kg daily in 2 divided doses. Max: 800 mg/day. >60 kg: 400 mg bid. Admin dose for three 28-day cycles w/ a 14-day drug-free interval in between each cycle. Neurocysticercosis Adult: <60 kg: 15 mg/kg daily in 2 divided doses (max: 800 mg/day) for 8-30 days. >60 kg: 400 mg bid for 8-30 days. Larva Migrans, Cutaneous & Trichuriasis 400 mg PO qDay x 3 days Larva Migrans, Visceral 400 mg PO BID x 5 days Fluke (Clonorchis Sinensis) 10 mg/kg PO qDay x7 days Gnathostomiasis, Microsporidiosis 400 mg BID x 21 days

Child Dose

Child: Usually PO 15 mg/kg/day (max 800 mg/day) q12h Oral Ascariasis, Enterobiasis, Trichuriasis, Hookworm infections Child: 1-2 years 200 mg as a single dose. OR 5 ml suspension 2 years 400 mg PO once as a single dose OR 10 ml suspension Max: 200 mg. Tapeworm infections Child: >2 years: 400 mg daily on an empty stomach for 3 consecutive days. Max: 400 mg daily; 1200 mg for 3 days. If patient is not cured after 3 weeks, a second course of treatment is needed. In cases of Hymenolepis nana infestations, retreatment in 10-21 days is recommended.

Renal Dose

N/A

Administration

Should be taken with food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.

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