Acliz PLUS - 25 MG

Tablet

Pack Size : 10 Tablet x 1 Strip

Generics : Meclizine + Pyridoxine

Manufacturer : Aristopharma Limited

Best Price * TK 30.00

* Delivery will be done in Dhaka city only.

Alternative Product

More Information About - Acliz PLUS - 25 MG

Description

Generic Name

Meclizine Hydrochloride + Pyridoxine Hydrochloride

Precaution

Prostate hypertrophy, obstruction of bladder neck, narrow angle glaucoma, pyloric stenosis. May impair ability to drive or operate machinery. Pregnancy. Lactation: Not known if excreted in milk; use caution

Indication

Nausea, vomiting, dizziness, motion sickness, radiation sickness and vertigo associated with diseases of vestibular motion sickness, radiation sickness and vertigo associated with diseases of vestibular system, morning sickness during pregnancy, drug induced nausea, vomiting induced by oral contraceptives or Estrogen preparations.

Contra Indication

Meclizine Hydrochloride and Pyridoxine Hydrochloride is contraindicated in patients who are hypersensitive to these ingredients.

Dose

N/A

Side Effect

Drowsiness, thickening of bronchial secretions, dry mouth, fatigue, blurred vision.

Pregnancy Category

Name : B+A

Description

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester. Adequate and well-controlled human studies have failed to demonstrate a risk to the fetus in the first trimester of pregnancy (and there is no evidence of risk in later trimesters).

Mode of Action

Meclozine blocks vasopressor response to histamine and has a slight blocking action against acetylcholine. It decreases excitability of the middle ear labyrinth and blocks conduction in the middle ear vestibular-cerebellar pathways. Pyridoxine is a water-soluble vitamin which functions in the metabolism of carbohydrates, proteins and fats. It is essential in Hb formation and GABA synthesis within the CNS. It also aids in the release of glycogen stored in the liver and muscles.

Interaction

Additive effects with CNS depressants, neuroleptics, anticholinergics, alcohol.

Pregnancy Category Note

N/A

Adult Dose

Oral Motion sickness Adult: 25-50 mg Meclizine 1 hr before travelling and repeat 24 hrly if needed. Vertigo and vestibular disorders Adult: 25-100 mg Meclizine daily in divided doses. Discontinue if there is no response after 1-2 wk of treatment. Radiation sickness: 50 mg Meclizine administered 2-12 hours prior to radiation treatment. Pyridoxine (vitamin B6) has been shown to be safe and effective in dosages of 50 to 200 mg per day.

Child Dose

Oral <12 years: Safety and efficacy not established

Renal Dose

N/A

Administration

May be taken with or without food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.