Ace PLUS - 65 mg

Tablet
Pack Size :   10 Tablet x 1 Strip
Best Price * TK  25.10
* Delivery will be done in Dhaka city only.

More Information About - Ace PLUS - 65 mg

Description

Generic Name

Paracetamol + Caffeine

Precaution

Use with caution in alcoholism, hepatic or renal disorder. The hazard of overdose is greater in those with non-cirrhotic alcoholic liver disease. Excessive intake of caffeine (e.g. coffee, tea and some canned drinks) should be avoided while taking this product.

Indication

Pain, Fever, Headache, Influenza, Migraine, Sore throat, Backache, Toothache, Rheumatic pain, Dysmenorrhea, Colds

Contra Indication

Paracetamol is contraindicated in patients with severe renal function impairment and hepatic disease (Viral Hepatitis). Known hypersensitivity to paracetamol or caffeine.

Dose

N/A

Side Effect

Haematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally. When the recommended paracetamol-caffeine dosing regimen is combined with dietary caffeine intake, the resulting higher dose of caffeine may increase the potential for caffeine-related adverse effects such as insomnia, restlessness, anxiety, irritability, headaches, gastrointestinal disturbances and palpitations.

Pregnancy Category

Name : C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Paracetamol exhibits analgesic action by peripheral blockage of pain impulse generation. It produces antipyresis by inhibiting the hypothalamic heat-regulating centre. Its weak anti-inflammatory activity is related to inhibition of prostaglandin synthesis in the CNS. Caffeine, a methylxanthine, is a phosphodiesterase inhibitor. It has an antagonistic effect at central adenosine receptors. It is a CNS and resp stimulant. It has bronchodilating and diuretic properties and it facilitates the performance of muscular work.

Interaction

May reduce serum levels w/ anticonvulsants (e.g. phenytoin, barbiturates, carbamazepine). May enhance the anticoagulant effect of warfarin and other coumarins w/ prolonged use. Accelerated absorption w/ metoclopramide and domperidone. May increase serum levels w/ probenecid. May increase serum levels of chloramphenicol. May reduce absorption w/ colestyramine w/in 1 hr of admin. May cause severe hypothermia w/ phenothiazine.

Pregnancy Category Note

Pregnancy category: C Lactation: Excreted in breast milk

Adult Dose

Oral Fever, headache, migraine, muscle ache, backache, toothache & menstrual pain. Adults : 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily.

Child Dose

Not recommended for children below 12 years. Child >12 years: 1-2 tablets every 4-6 hours. Maximum dose: 8 tablets daily.

Renal Dose

N/A

Administration

May be taken with food.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.

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