More Information About - Tervent 100ml Syp. 1.5mg/5ml
Description
Generic Name
Terbutaline Sulphate
Precaution
Patient w/ thyrotoxicosis, HTN, DM, ketoacidosis, CV disorders (e.g. ischaemic heart disease), convulsive disorders, coronary insufficiency or associated arrhythmias. Childn. Pregnancy and lactation. Monitoring Parameters Monitor cardiorespiratory function, serum K and glucose levels;
Lactation: Distributed into breast milk, but in amounts generally considered insufficient to affect nursing infants (AAP Committee states compatible with nursing)
Indication
Acute bronchospasm
Contra Indication
Hypersensitivity to sympathomimetics. Any condition of mother or foetus in which prolongation of pregnancy is dangerous.
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Terbutaline is a direct-acting sympathomimetic which relaxes bronchial smooth muscle by selective action on beta2 receptors. It also decreases uterine contractility.
Interaction
Antagonised effects of beta-blockers. Increased risk of hypokaelemia with xanthine derivatives, corticosteriods and diuretics; increased risk of arrhythmias with inhaled anaesthetics, sympathomimetics.
Pregnancy Category Note
Pregnancy Category: C
Lactation: Distributed into breast milk, but in amounts generally considered insufficient to affect nursing infants (AAP Committee states compatible with nursing)
Adult Dose
Oral
Acute bronchospasm
Adult: Initiate at 2.5 mg three/four times daily
Maintenance: 5 mg three times daily q6hr while patient is awake; reduce dose to 2.5 mg q6hr
Not to exceed 15 mg/Day
Child Dose
Oral
Acute bronchospasm
Child: <12 years: 0.05 mg/kg three times daily initially; increase PRN, not to exceed 5 mg/day
12-15 years: 2.5 mg PO q6hr 3 times daily; not to exceed 7.5 mg/day
>15 years: 5 mg/dose PO q8hr three times daily; reduce dose to 2.5 mg q6hr; not to exceed 15 mg/24hr
Renal Dose
Renal Impairment
GFR <50 mL/min: reduce dose by 50%
GFR >50mL/min: Dose adjustment not necessary
Administration
May be taken with or without food.
Disclaimer
The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.