Pregnancy and lactation. Avoid contact with eyes. Discontinue if irritation or sensitisation occurs. Cross-sensitisation with other imidazole derivatives may occur.
Lactation: distributed into milk; use with caution in nursing women
Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.
Mode of Action
Oxiconazole, a synthetic azole antifungal, is usually fungistatic but may be fungicidal in high concentrations. It exerts its antifungal activity by interfering w/ ergosterol synthesis and altering cellular membranes. It also has some antibacterial activity against aerobic gm+ve organisms.
Interaction
N/A
Pregnancy Category Note
N/A
Adult Dose
Topical/Cutaneous
Tinea cruris; Tinea corporis; Tinea pedis
Adult: Apply 1% cream once or bid.
Duration of treatment: 2 wk for tinea corporis and tinea cruris or 1 mth for tinea pedis.
Pityriasis versicolor
Adult: As 1% cream: Apply to affected areas once daily for 2 wk.
Child Dose
N/A
Renal Dose
N/A
Administration
N/A
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