Patients with known hypersensitivity to magnesium and aluminium. It is also contraindicated in patients with impaired renal functions.
Dose
N/A
Side Effect
Aluminum oxide
Chalky taste,Constipation,Fecal impaction,Stomach cramps
Frequency Not Defined
Aluminum oxide
Nausea,Vomiting,Aluminum intoxication,Hypophosphatemia,Osteomalacia,
Magnesium oxide
Diarrhea,Hypermagnesemia
Pregnancy Category
Name :
C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Magaldrate is a hydroxymagnesium aluminate complex that is rapidly converted in gastric acid to magnesium and aluminium hydroxide, which is poorly absorbed and provides a sustained antacid effect with balanced efects on intestinal motility; increases lower esophageal sphincter tone and inhibits smooth muscle contraction and gastric emptying.
Simethicone allows gas bubbles in the stomach and intestines to come together more easily, which allows for easier passage of gas.
Interaction
Magaldrate may negatively influence drugs like tetracyclines, benzodiazepines, and indomethacin. High doses or prolonged usage may lead to an increment of defecation and a reduction in feces consistence. In some cases it can alter the functionality of the gastrointestinal tract, occasionally provoking constipation or diarrhea.
Pregnancy Category Note
N/A
Adult Dose
Oral
Adult
Tablet: 1-3 tablet, after meals and at bed time.
Child Dose
Oral
Children 12 years and older:
Tablet: 1-3 tablet, after meals and at bed time.
Renal Dose
N/A
Administration
Take between meals & at bedtime.
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