Gentacin

Ointment

Pack Size : 1 ointment x 1 Packet

Generics : Gentamicin 0.3% E/E prep

Manufacturer : Acme Laboratories Ltd.

Best Price * TK 9.75

* Delivery will be done in Dhaka city only.

Alternative Product

Drops Genacyn 300 mg/100 ml Square Pharmaceuticals Ltd.

Tk 32.12

Drops Genta 10ml Renata Limited

Tk 31.93

More Information About - Gentacin

Description

Generic Name

Gentamicin 0.3% E/E prep

Precaution

Concurrent use of neuromuscular blocking agents; myasthenia gravis, parkinsonism; conditions predisposing to ototoxicity and nephrotoxicity; lactation. Monitor plasma concentrations of gentamicin in patients receiving high doses or prolonged courses, in infants, elderly, patients with renal impairment, cystic fibrosis or significant obesity. Monitor auditory and renal functions. Lactation: safety in nursing infants unknown

Indication

Superficial ophthalmic infections, Otitis externa,

Contra Indication

History of hypersensitivity to aminoglycoside; pregnancy; hepatic impairment, perforated ear drum.

Dose

N/A

Side Effect

Allergic contact dermatitis, Transient irritation, burning, stinging, Increased redness, lacrimation

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Gentamicin is an aminoglycoside that binds to 30s and 50s ribosomal subunits of susceptible bacteria disrupting protein synthesis, thus rendering the bacterial cell membrane defective.

Interaction

Additive effect w/ other neurotoxic and/or nephrotoxic drugs including cephalosporins, methicillin, amphotericin B, ciclosporin, cisplatin, potent diuretics (e.g. ethacrynic acid, furosemide) and neuromuscular blocking agents (e.g. succinylcholine, tubocurarine). May potentiate the effect of anticoagulants (e.g. warfarin, phenindione). May antagonise the effect of neostigmine and pyridostigmine. Increased risk of hypocalcaemia w/ bisphosphonates. Increased risk of neuromuscular blockade w/ botulinum toxin. Indometacin may increase the plasma concentration of gentamicin in neonates.

Pregnancy Category Note

Pregnancy Category: C Lactation: safety in nursing infants unknown

Adult Dose

Ophthalmic Superficial ophthalmic infections Adult: As eye drops: Instill 1-2 drops into affected eye up to 6 times daily. For severe infections, initially, 1-2 drops every 15 min, reducing the frequency gradually as the infection is controlled. As eye oint: Place a small amount into the conjunctival sac 2-3 times daily. Otic/Aural Otitis externa Adult: As ear drops: Instill 2-3 drops in the affected ear 3-4 times a day and at night.

Child Dose

Ophthalmic Superficial ophthalmic infections Child: As eye drops: Instill 1-2 drops into affected eye up to 6 times daily. For severe infections, initially, 1-2 drops every 15 min, reducing the frequency gradually as the infection is controlled. As eye oint: Place a small amount into the conjunctival sac 2-3 times daily. Otic/Aural Otitis externa Child: As ear drops: Instill 2-3 drops in the affected ear 3-4 times a day and at night.

Renal Dose

N/A

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.