Microgest 100 mg Soft Gelatin Cap. 100mg

Capsule

Pack Size : 10 Capsule x 1 Strip

Generics : Progesterone

Manufacturer : Renata Limited

Best Price * TK 160.00

* Delivery will be done in Dhaka city only.

Alternative Product

Capsule Microgest 100 mg Soft Gelatin Cap Renata Limited

Tk 16.00

Capsule Microgest 200 mg Soft Gelatin Cap Renata Limited

Tk 32.00

Capsule Microgest 200 mg Soft Gelatin Cap. 200mg Renata Limited

Tk 32.00

More Information About - Microgest 100 mg Soft Gelatin Cap. 100mg

Description

Generic Name

Progesterone

Precaution

Family history of breast cancer and or DVT/PE, current/history of depression, endometriosis, DM, HTN, bone mineral density changes, renal/hepatic impairment, bone metabolic disease, SLE; conditions exacerbated by fluid retention (eg, migraine, asthma, epilepsy). Discontinue if the following develop jaundice, visual problems (may cause contact lens intolerance), any signs of VTE, migraine with unusual severity, significang blood pressure increase, severe depression, increased risk of thromboembolic complications after surgery. Discontinue 4 week before major surgery or prolonged immobilization. Patients on warfarin, oral anticoagulants (increase in anticoagulant dose may be warranted). Some studies link OCP use with increased risk of breast cancer, whereas other studies have not shown a change in risk. Increased risk of cervical cancer with OCP use, however HPV remains as main risk factor for this cancer. Evidence suggests long-term use of OCPs, 5 or more years, may be associated with increased risk. Increased risk of liver cancer with OCP use; risk increases with longer duration of OCP use. May cause dizziness; use caution when driving a motor vehicle or operating machinery Increased risk of developing probable dementia in postmenopausal women >65 years of age reported Use with caution in patients with history of depression Use with caution in patients with diseases that could become exacerbated by fluid retention including epilepsy, migraine, renal dysfunction, diabetes, or asthma

Indication

Premenstrual syndrome, Contraception, Menopausal HRT, Amenorrhoea, Recurrent miscarriage

Contra Indication

Hypersensitivity; thrombophloebitis; cerebral apoplexy; severe hepatic impairment; undiagnosed vag bleeding, incomplete abortion, hormone-dependent carcinoma, as a diagnostic test for pregnancy; pregnancy. History or current high risk of arterial disease.

Dose

N/A

Side Effect

>10% Headache (10-31%),Breast tenderness (16-27%),Dizziness (15-24%),Abdominal pain (10-20%),Depression (19%),Breast pain (6-16%),Viral disease (7-12%) 1-10% Vaginal discharge (10%),Fatigue (8-9%),Nausea (8%),Mood swings (6%) Frequency Not Defined Dementia, probable(postmenopausal women >65 years of age, possible association),Anorexia,Weakness,Weight change (less common than with synthetic progestins),Vomiting,Edema,DVT (postmenopausal women 50-79 years of age),Thrombophlebitis,Myocardial infarction (postmenopausal women 50-79 years of age),Stroke (postmenopausal women 50-79 years of age),Pulmonary emboli (postmenopausal women 50-79 years of age),Amenorrhea (less common than with synthetic progestins),Breakthrough bleeding (less common than with synthetic progestins),Change in menstrual flow(less common than with synthetic progestins),Spotting (less common than with synthetic progestins),Breast changes (less common than with synthetic progestins),Invasive breast cancer(postmenopausal women 50-79 years of age),Cholestatic jaundice,Vaginal candidiasis,General pruritus,Ectopic pregnancy

Pregnancy Category

Name : B

Description

Animal reproduction studies have failed to demonstrate a risk to the fetus and there are no adequate and well-controlled studies in pregnant women OR Animal studies have shown an adverse effect, but adequate and well-controlled studies in pregnant women have failed to demonstrate a risk to the fetus in any trimester.

Mode of Action

Progesterone is the main hormone secreted by corpus luteum. It induces secretory changes in the endometrium, promotes mammary gland development, relaxes uterus, blocks follicular maturation and ovulation, and maintains pregnancy.

Interaction

N/A

Pregnancy Category Note

Pregnancy Category: B Lactation: Possibly safe; use caution

Adult Dose

Oral Progestogen component of menopausal hormonal replacement therapy. Adult: 200 mg daily as a single daily dose at night for 12-14 days of each mth. Amenorrhoea Adult: 400 mg daily for 10 days. Dysfunctional uterine bleeding. Adult: 400 mg daily for 10 days. Prevention of Endometrial Hyperplasia. Adult: 200 mg PO at night for 12 days sequentially per 28-day cycle Vaginal Gel Dysfunctional uterine bleeding. Adult: 45 mg every other day from the 15th-25th day of the cycle. May increase dose to 90 mg in non-responders. Amenorrhoea. Adult: 45 mg every other day from the 15th-25th day of the cycle. May increase dose to 90 mg in non-responders.

Child Dose

N/A

Renal Dose

N/A

Administration

N/A

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.