A-Migel 15gm

Gel

Pack Size : 1 Tube x 1 Bottle

Generics : Miconazole 2% Oral Gel

Manufacturer : Acme Laboratories Ltd.

Best Price * TK 52.16

* Delivery will be done in Dhaka city only.

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More Information About - A-Migel 15gm

Description

Generic Name

Miconazole 2% Oral Gel

Precaution

Caution is required particularly in infants & young children to ensure that the gel does not obstruct the throat. Lactation: Unknown whether distributed in breast milk, caution advised

Indication

Oropharyngeal candidiasis, Oral thrush, Denture stomatitis, Fungal infections of the mouth, Throat and gut, Angular cheilitis, Dermatomycoses, Tinea pedis, Tinea corporis, Tinea cruris, Tinea versicolor

Contra Indication

Miconazole Oral Gel is contraindicated in patients with known hypersensitivity to any of its components and in patients with liver dysfunction.

Dose

N/A

Side Effect

1-10% Diarrhea (6%),Nausea (4.6%),Headache (5%),Dysgeusia (2.9%),Upper abdominal pain (2.5%),Vomiting (2.5%)

Pregnancy Category

Name : C

Description

Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks

Mode of Action

Miconazole inhibits ergosterol synthesis thus damaging fungal cell wall membrane and increases its permeability, allowing leakage of nutrients.

Interaction

May increase anticoagulant effect of warfarin. May increase or prolong the effect of the following drugs: Oral hypoglycaemics (e.g. sulfonylureas), phenytoin, HIV protease inhibitors (e.g. saquinavir), antineoplastic agents (e.g. vinca alkaloids, busulfan, docetaxel), Ca channel blockers (e.g. dihydropyridines, verapamil), immunosuppressive agents (e.g. ciclosporin, tacrolimus, sirolimus), carbamazepine, cilostazol, buspirone, disopyramide, alfentanil, sildenafil, alprazolam, brotizolam, midazolam IV, rifabutin, methylprednisolone, trimetrexate, ebastine and reboxetine. Potentially Fatal: Increased risk of cardiac arrhythmia w/ astemizole, cisapride, dofetilide, halofantrine, mizolastine, pimozide, quinidine, sertindole, terfenadine. May increase exposure to ergot alkaloids leading to ergotism. May increase the risk of rhabdomyolysis w/ HMG-CoA reductase inhibitors (e.g. simvastatin and lovastatin). May increase the effect of triazolam and oral midazolam.

Pregnancy Category Note

N/A

Adult Dose

Mouth/Throat Oropharyngeal candidiasis, Intestinal candidiasis Adult: The usual dose is 15 mg/kg/day in divided doses. One or two tea spoonfuls (5-10 ml) of gel four times daily. Continue treatment for at least 1 wk after symptoms have disappeared. Localised lesions of mouth: Smear small amount on affected area with clean finger 4 times daily for 5-7 days.

Child Dose

Mouth/Throat Oropharyngeal candidiasis Children aged 6 years and over: One tea-spoonful (5 ml) of gel four times daily. Children aged 2-6 years: One tea-spoonful (5 ml) of gel twice daily. Infants under 2 years: Half tea-spoonful (2.5 ml) of gel twice daily. Continue treatment for at least 1 wk after symptoms have disappeared. Localised lesions of mouth: Smear small amount on affected area with clean finger 4 times daily for 5-7 days.

Renal Dose

N/A

Administration

Apply on oral lesions and retain in the mouth as long as possible before swallowing. For localised lesions of the mouth, a small amount of gel may be applied directly to the affected area with a clean finger.

Disclaimer

The information provided herein are for informational purposes only and not intended to be a substitute for professional medical advice, diagnosis, or treatment. Please note that this information should not be treated as a replacement for physical medical consultation or advice. Great effort has been placed to provide accurate and comprehensive data. However, Medicart along with its authors and editors make no representations or warranties and specifically disclaim all liability for any medical information provided on the site. The absence of any information and/or warning to any drug shall not be considered and assumed as an implied assurance of the Company.