The active substances Timolol/ Bimatoprost may be absorbed systemically. Due to the beta-adrenergic component, Timolol, the same types of cardiovascular, pulmonary and other adverse reactions as seen with systemic beta-blockers may occur. Caution should be exercised in treating patients with severe or unstable and uncontrolled cardiovascular Disease.
Indication
Reduction of intra-ocular pressure in adult patients with, open-angle glaucoma, ocular hypertension
Contra Indication
It is contraindicated in patients with known hypersensitivity to any ingredient of this formulation.
Dose
N/A
Side Effect
26%
Ocular hyperemia
5-10%
Decreased visual acuity, eye discomfort, foreign body sensation, pain and pruritis
Pregnancy Category
Name :
C
Description
Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks
Mode of Action
Interaction
There is a potential for bradycardia when ophthalmic beta-blockers solution is administered concomitantly with oral calcium channel blockers, guanethidine, beta-adrenergic blocking agents, parasympathomimetics, anti-arrhythmic and digitalis glycosides. Concomitant ocular medications should be administered at least 5 min apart from the instillation of this Eye Drops.
Pregnancy Category Note
N/A
Adult Dose
Adult:
Eye drop: The recommended dose is one drop in the affected eye(s) once-daily.
Child Dose
Safety and effectiveness in pediatric patients have not been established.
Renal Dose
N/A
Administration
N/A
Disclaimer
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