This combination of a nasal decongestant, a histamine H1-receptor antagonist, and an antitussive combination is suggested for the symptomatic alleviation of upper respiratory tract diseases accompanied by non-productive cough.
The preparation is a mixture of antitussive, decongestant and antihistamine. Dextromethorphan is a safe and effective non-narcotic antitussive, which has a central effect on the cough center in the spinal cord. Although it is structurally related to morphine, it has no analgesic or addictive properties and usually has little sedation. Phenylephrine is a decongestant that constricts blood vessels in the nasal passages. It is used to treat congestion of the nasal cavity and sinuses of tubes that drain fluid from the inner ear. Triprolidine may alleviate symptoms when it is believed to be fully or partially dependent on triggered histamine release. It is an effective competitive antagonist of the pyrrolidine histamine H1 receptor, with mild central nervous system inhibitory properties, which can cause drowsiness.
Adults & Children over 12 years: 1 teaspoonful 4 times a day.
6-12 years: 1/2 teaspoonful 4 times a day.
A physician's advice should be obtained before administering this combination to children less than 6 years.
This combination is contraindicated in patients with a known hypersensitivity to Dextromethorphan, Phenylephrine or Triprolidine as well as in persons under treatment with Monoamine Oxidase Inhibitor within 2 weeks of stopping such treatment.
Dextromethorphan has a few known side effects, including sleepiness. Prostatic enlargement might have had a role in the development of the disease.
There is no information on the usage of this combination during pregnancy or lactation.
This combo has the potential to make you sleepy. It has the potential to impede the patient's ability to drive and operate machinery. Despite the lack of objective evidence, users of this syrup should avoid using alcohol or other centrally acting sedatives at the same time. In individuals with hypertension, heart disease, diabetes, hyperthyroidism, increased intraocular pressure, or prostatic enlargement, caution should be used as with other sympathomimetic drugs. Unless otherwise instructed by a physician, this combination should not be used for persistent or chronic cough, such as that caused by smoking, asthma, or emphysema, or cough that is accompanied by copious secretion.
Protect from light, store in a cool and dry place. Keep out of the reach of children.
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