Generic Name

Tolperisone Hydrochloride

Precaution

In case of children, the prescribed dose and duration of treatment should closely be observed.

Indication

Painful muscle spasm associated with disorders of the locomotor system: Low back pain, sciatica, overstrain of joints, osteoarthritis, rheumatoid arthritis, herniated disc, spondylosis, nerve root compression caused by osteoporosis, soft tissue inflammation (bursitis, periarthritis, humeroscapsularis). Muscle spasticity associated with neurological conditions: Stroke induced hemiparesis or hemiplegia, pyramidal tract lesion, multiple sclerosis, myelopathies, encephalomyelitis, spinal automatisms, paralysis spinalis spastica, cerebral palsy. Decreased peripheral circulation as seen in: Atherosclerosis obliterans, endarteritis obliterans, thromboangitis obliterans, Raynaud's disease, acrocyanosis, intermittent angioneurotic dysbasia. Special paediatric indications: Little's disease (spastic paralysis) and other encephalopathies accompanied by dystonia. Rehabilitation: Treatment after limb fractures followed by long term fixation, postoperative therapy of traumatological and orthopedic limb surgery, rehabilitation of hemiplegic patients.

Contra Indication

Hypersensitivity to any component of the product Myasthenia gravis, Nursing mother

Dose

N/A

Side Effect

Sometimes, muscular weakness, headache, nausea, vomiting and rarely hypersensitivity reactions may occur as side effects.

Pregnancy Category

Mode of Action

Tolperisone is a centrally acting muscle relaxant.

Interaction

Methocarbamol. Tolperisone HCl.

Pregnancy Category Note

N/A

Adult Dose

Oral Spasticity ; Muscle spasms Adult: 50-150 mg tid. Intramuscular Adult: One ampoule twice daily. Injection should be given slowly.

Child Dose

Oral Spasticity ; Muscle spasms Child: <6 yr: 5 mg/kg daily in 3 divided doses; 6-14 yr: 2-4 mg/kg daily in 3 divided doses.

Renal Dose

N/A

Administration

Should be taken with food.